Intracellular Ca<sup>2+</sup> Modulators

Calcium Homeostasis Modulators

Intracellular Ca2+ Modulators

Calcium homeostasis modulator 1 (CALHM1) is a cerebral Ca2+ channel component responsible for controlling intracellular Ca2+ levels and Ab metabolism. CALHM1 is a three transmembrane glycoprotein, mostly localized to the endoplasmic reticulum (ER) although it can be detected at the plasma membrane. A functional channel is formed by multiple subunits which has some structural similarities to the NMDA receptor. It is expressed in all brain regions.

Displaying 1 to 13 products (out of 13 products)
  • A23187

    Widely Used Ca2+ Ionophore

    Cat # A-600
    Source Natural
    MW 523.6
  • Anhydroryanodine

    A Non Active Analogue of Ryanodine

    Cat # A-510
    Source Natural
    MW 475.54
  • Cyclopiazonic Acid

    A Potent Inhibitor of Intracellular Ca2+-ATPase Pump

    Cat # C-750
    Source Natural
    MW 336.4
    Target SERCA pump
  • Imperatoxin A

    A Ryanodine Receptor Modulator

    Cat # STI-333
    MW 3758 Da.
    Target Ryanodine receptors
  • Ionomycin calcium salt

    A Potent and Selective Ca2+ Ionophore

    Cat # I-700
    Source Natural
    MW 747.08
  • Maurocalcine

    A Ryanodine Receptor 1, 2 & 3 Modulator

    Cat # RTM-100
    MW 3864 Da.
    Target Ryanodine receptors
  • NS-1619

    Selective and Potent Enhancer of KCa1.1 Channels and an Inhibitor of SERCA Pumps

    Cat # N-105
    Source Synthetic
    MW 362.2
    Target KCa1.1 K+ channels, SERCA pumps
  • Ochratoxin A

    A Potent Modulator of Ca2+ ATPase Pump

    Cat # O-400
    Source Natural
    MW 403.8
    Target SERCA pump
  • Paxilline

    A Mycotoxin Blocker of KCa1.1 (BK) Channels and SERCA Pumps

    Cat # P-450
    Source Natural
    MW 435.6
    Target KCa K+ channels, SERCA pump
  • Ryanodine

    A Blocker of Ryanodine Receptors

    Cat # R-500
    Source Natural
    MW 493.5
    Target Ryanodine receptors
  • tBuBHQ

    A Potent Inhibitor of Sarcolasmic Reticulum Ca2+ ATPase

    Cat # T-220
    Source Synthetic
    MW 222.33
    Target SERCA
  • Thapsigargin

    A Potent and Cell-Permeable Inhibitor of SERCA Pump Ca2+-ATPase/an Intracellular Ca2+ Mobilizer

    Cat # T-650
    Source Natural
    MW 650.7
    Target SERCA
  • Thapsigargin Epoxide

    A Nonactive Analogue of Thapsigargin

    Cat # T-670
    Source Natural
    MW 632.75
    Target SERCA

* See product page

Displaying 1 to 13 products (out of 13 products)