Modulators

Neurotrophin Receptors and Co-Receptors

Modulators

BDNF and NT-4 belong to the neurotrophin family which also includes NGF and NT-3. These neurotrophins bind two groups of receptors. The p75NTR receptor is common to all four neurotrophins and is a member of the tumor necrosis factor receptor family. The tropomyosin-related kinase (Trk) receptors are receptor tyrosine kinases (RTKs) and three receptors form this family: TrkA, TrkB, and TrkC. TrkA is activated by NGF binding, TrkB by that of BDNF and NT-4, while TrkC is stimulated by the binding of NT-3.

Displaying 1 to 17 products (out of 17 products)
  • α-Asarone

    An Antagonist of NaV Channels, GABA(A) Receptors, NMDA Receptors and an Inhibitor of TrkB Receptor

    Cat # A-260
    Source Natural
    MW 208.3
    Target NaV channels, GABA(A) receptors, TrkB receptors, NMDA receptors
    • Lyophilized Powder
  • ANA-12

    A Selective Antagonist of TrkB Receptor

    Cat # A-215
    Source Synthetic
    MW 407.49
    Target TrkB receptor
    • Lyophilized Powder
  • AZD-1332

    A Potent and Selective Inhibitor of TrkA, TrkB, TrkC Receptors

    Cat # A-495
    Source Synthetic
    MW 391.8
    Target TrkA, TrkB, TrkC receptors
    • Lyophilized Powder
  • GNF 5837

    A Potent pan-Trk (Neurotrophin Receptor) Inhibitor

    Cat # G-145
    Source Synthetic
    MW 535.49
    Target TrkA, TrkB, TrkC receptors
    • Lyophilized Powder
  • GW-2580

    An Inhibitor of Trk Receptors and cFMS/CSF-1 Receptor Kinases 

    Cat # G-255
    Source Synthetic
    MW 366.41
    Target CSF-1R receptor, Trk receptor
    • Lyophilized Powder
  • GW441756

    A Potent Inhibitor of TrkA

    Cat # G-190
    Source Synthetic
    MW 275.3
    Target TrkA receptors
    • Lyophilized Powder
  • GW441756 hydrochloride

    A Potent Inhibitor of TrkA

    Cat # G-191
    Source Synthetic
    MW 311.8
    Target TrkA receptors
    • Lyophilized Powder
  • K252a

    A Potent Inhibitor of Protein Kinase A, Protein Kinase C, and Protein Kinase G

    Cat # K-150
    Source Natural
    MW 467.5
    Target

    Protein kinases

    • Lyophilized Powder
  • BDNF Basic Research Pack

    All You Need for BDNF Research

    Cat # ESB-600
    • Lyophilized Powder
    • Antigen Incl.
  • BDNF Premium Research Pack

    All You Need for BDNF Research

    Cat # ESP-600
    • Lyophilized Powder
    • Antigen Incl.
  • BDNF Deluxe Research Pack

    All You Need for BDNF Research

    Cat # ESD-600
    • Lyophilized Powder
    • Antigen Incl.
  • Human NGF Basic Research Pack

    All You Need for NGF Research

    Cat # ESB-650
    • Lyophilized Powder
    • Antigen Incl.
  • Human NGF Premium Research Pack

    All You Need for NGF Research

    Cat # ESP-650
    • Lyophilized Powder
    • Antigen Incl.
    • Sterile & Endotoxin Free
  • Human NGF Deluxe Research Pack

    All You Need for NGF Research

    Cat # ESD-650
    • Lyophilized Powder
    • Antigen Incl.
  • Mouse NGF Basic Research Pack

    All You Need for NGF Research

    Cat # ESB-651
    • Lyophilized Powder
    • Antigen Incl.
  • Mouse NGF Premium Research Pack

    All You Need for NGF Research

    Cat # ESP-651
    • Lyophilized Powder
    • Antigen Incl.
  • Mouse NGF Deluxe Research Pack

    All You Need for NGF Research

    Cat # ESD-651
    • Lyophilized Powder
    • Antigen Incl.

* See product page

Displaying 1 to 17 products (out of 17 products)