Modulators

Pro-Neurotrophin Receptors

Modulators

Neurotrophins, like many growth factors, are expressed as precursor proteins which are then truncated and further modified to yield the mature form. The presence of highly conserved sequences in the prodomains of different neurotrophins made it clear that the prodomain must have some biological role and is not solely present as a protein folding chaperone. Proneurotrophins mediate their signaling by binding to p75NTR and Sortilin receptors.

Displaying 1 to 15 products (out of 15 products)
  • α-Asarone

    An Antagonist of NaV Channels, GABA(A) Receptors, NMDA Receptors and an Inhibitor of TrkB Receptor

    Cat # A-260
    Source Natural
    MW 208.3
    Target NaV channels, GABA(A) receptors, TrkB receptors, NMDA receptors
    • Lyophilized Powder
  • ANA-12

    A Selective Antagonist of TrkB Receptor

    Cat # A-215
    Source Synthetic
    MW 407.49
    Target TrkB receptor
    • Lyophilized Powder
  • GNF 5837

    A Potent pan-Trk (Neurotrophin Receptor) Inhibitor

    Cat # G-145
    Source Synthetic
    MW 535.49
    Target TrkA, TrkB, TrkC receptors
    • Lyophilized Powder
  • GW441756

    A Potent Inhibitor of TrkA

    Cat # G-190
    Source Synthetic
    MW 275.3
    Target TrkA receptors
    • Lyophilized Powder
  • GW441756 hydrochloride

    A Potent Inhibitor of TrkA

    Cat # G-191
    Source Synthetic
    MW 311.8
    Target TrkA receptors
    • Lyophilized Powder
  • K252a

    A Potent Inhibitor of Protein Kinase A, Protein Kinase C, and Protein Kinase G

    Cat # K-150
    Source Natural
    MW 467.5
    Target

    Protein kinases

    • Lyophilized Powder
  • BDNF Basic Research Pack

    All You Need for BDNF Research

    Cat # ESB-600
    • Lyophilized Powder
    • Antigen Incl.
  • BDNF Premium Research Pack

    All You Need for BDNF Research

    Cat # ESP-600
    • Lyophilized Powder
    • Antigen Incl.
  • BDNF Deluxe Research Pack

    All You Need for BDNF Research

    Cat # ESD-600
    • Lyophilized Powder
    • Antigen Incl.
  • Human NGF Basic Research Pack

    All You Need for NGF Research

    Cat # ESB-650
    • Lyophilized Powder
    • Antigen Incl.
  • Human NGF Premium Research Pack

    All You Need for NGF Research

    Cat # ESP-650
    • Lyophilized Powder
    • Antigen Incl.
    • Sterile & Endotoxin Free
  • Human NGF Deluxe Research Pack

    All You Need for NGF Research

    Cat # ESD-650
    • Lyophilized Powder
    • Antigen Incl.
  • Mouse NGF Basic Research Pack

    All You Need for NGF Research

    Cat # ESB-651
    • Lyophilized Powder
    • Antigen Incl.
  • Mouse NGF Premium Research Pack

    All You Need for NGF Research

    Cat # ESP-651
    • Lyophilized Powder
    • Antigen Incl.
  • Mouse NGF Deluxe Research Pack

    All You Need for NGF Research

    Cat # ESD-651
    • Lyophilized Powder
    • Antigen Incl.

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Displaying 1 to 15 products (out of 15 products)