Guinea Pig-Raised Antibodies: Antibodies raised in guinea pig can be used with any non-guinea pig second species antibodies (e.g. antibodies raised in mouse, rabbit, goat, etc.) in complex immunostaining or immunoprecipitation protocols. Our line of guinea pig raised antibodies can be combined with any of our rabbit-raised or ATTO-conjugated antibodies in complex immunostaining protocols.
KV1.3 channels are widely expressed in the brain, lung and osteoclasts and in several cell populations of hematopoietic origin. KV1.3 expression/function in T-lymphocytes is responsible for maintaining the resting potential in quiescent cells and regulating Ca2+ signaling, indispensable for normal T-lymphocyte activation.