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Biotinylated Toxins

Voltage-Gated K+ Channels

K+ selective channels are some of the most widespread ion trafficking molecules in living organisms, with more than 70 genes encoding different K+ channels in humans. Kchannels fall into one of the two classical categories of delayed rectifier (DR) and A-type. Delayed rectifier was the original name attributed to voltage-dependent Kchannels due to their delayed activation in squid giant axons. A-type channels are low voltage-activated, fast inactivating (therefore, transient) K+ channels. Specific Ktoxins are often used to dissect the particular contribution of different subunits to native currents.

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  • Stichodactyla Toxin-Biotin

    Biotinylated ShK Conjugate for Sensitive Detection of KV Channels

    Cat # STS-400-B
    MW 4563 Da
    Target KV1.1, KV1.3, KV1.4, KV1.6 channels
    • Bioassay Tested

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