Cardiac Arrhythmia

Cardiac Arrhythmia

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

245 Results
  • (Rac)-TTA-P2
    Bioassay Tested
    (Rac)-TTA-P2
    A Blocker of T-Type CaV Channels
    • Product Code: T-155
    • Short Description: A Blocker of T-Type CaV Channels
    • CAS No.: 918430-49-6
    • MW: 431
  • Aa1 Toxin
    Bioassay Tested
    Aa1 Toxin
    A potent and selective blocker of KV4 (A-type) voltage-gated potassium channels
    • Product Code: RTA-400
    • Short Description: A potent and selective blocker of KV4 (A-type) voltage-gated potassium channels
    • Applications: Electrophysiology
    • MW: 3868 Da
  • Agitoxin-2-Cys-TAMRA
    Bioassay Tested
    Agitoxin-2-Cys-TAMRA
    A fluorescent probe for imaging and sensitive detection of KV1.3, KV1.1, and KV1.6 voltage-gated potassium channels
    • Product Code: RTA-420-T
    • Short Description: A fluorescent probe for imaging and sensitive detection of KV1.3, KV1.1, and KV1.6 voltage-gated potassium channels
    • Label: TAMRA
    • Applications: Electrophysiology, Fluorescence staining
    • MW: 4673 Da
  • AmmTx3 Toxin
    Bioassay Tested
    AmmTx3 Toxin
    A specific blocker of KV channels (subtypes KV4.2 and KV4.3) that selectively targets native neuronal A-type K+ currents
    • Product Code: STA-305
    • Short Description: A specific blocker of KV channels (subtypes KV4.2 and KV4.3) that selectively targets native neuronal A-type K+ currents
    • Applications: Electrophysiology
    • MW: 3822 Da
  • Anti-CACNA2D1 (Ca<sub>V</sub>α2δ1) (extracellular) Antibody
    KO Validate'
    Anti-CACNA2D1 (CaVα2δ1) (extracellular) Antibody
    A Rabbit Polyclonal Antibody to CACNA2D1 (CaVα2δ1 Subunit)
    • Product Code: ACC-015
    • Short Description: A Rabbit Polyclonal Antibody to CACNA2D1 (CaVα2δ1 Subunit)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Mouse
    • Applications: Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence
    • Target: Voltage-dependent Ca2+ channel subunit alpha-2/delta-1, L-type calcium channel alpha 2 polypeptide, Dihydropyridine-sensitive L-type calcium channel alpha-2/delta subunit
  • Anti-CACNB2 Antibody
    Anti-CACNB2 Antibody
    A Rabbit Polyclonal Antibody to CACNB2 (CaVβ2) Subunit
    • Product Code: ACC-105
    • Short Description: A Rabbit Polyclonal Antibody to CACNB2 (CaVβ2) Subunit
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: CaVβ2, Voltage-dependent L-type calcium channel subunit beta-2, CACNLB2, CAB2, CACB2, Lambert-Eaton myasthenic syndrome antigen B, MYSB
  • Anti-CACNB2-ATTO Fluor-594 Antibody
    Anti-CACNB2-ATTO Fluor-594 Antibody
    A Rabbit Polyclonal Antibody to CACNB2 (CaVβ2) Conjugated to the Fluorescent Dye ATTO-594
    • Product Code: ACC-105-AR
    • Short Description: A Rabbit Polyclonal Antibody to CACNB2 (CaVβ2) Conjugated to the Fluorescent Dye ATTO-594
    • Host: Rabbit
    • Label: ATTO 594
    • Reactivity: Rat, Mouse
    • Applications: Immunofluorescence, Immunohistochemistry
    • Target: CaVβ2, Voltage-dependent L-type calcium channel subunit beta-2, CACNLB2, CAB2, CACB2, Lambert-Eaton myasthenic syndrome antigen B, MYSB
  • Anti-Ca<sub>V</sub>1.1 (CACNA1S) (extracellular) Antibody
    Anti-CaV1.1 (CACNA1S) (extracellular) Antibody
    A Rabbit Polyclonal Antibody to CaV1.1 (CACNA1S) Channel
    • Product Code: ACC-314
    • Short Description: A Rabbit Polyclonal Antibody to CaV1.1 (CACNA1S) Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Voltage-dependent L-type calcium channel subunit α1S, CACH1, CACN1, CACH1B, CACNL1A3
  • Anti-Ca<sub>V</sub>1.2 (CACNA1C) (extracellular) Antibody
    Anti-CaV1.2 (CACNA1C) (extracellular) Antibody
    A Rabbit Polyclonal antibody to CaV1.2 (extracellular)
    • Product Code: ACC-130
    • Short Description: A Rabbit Polyclonal antibody to CaV1.2 (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunohistochemistry
    • Target: Voltage-dependent L-type calcium channel subunit alpha-1C, Calcium Voltage-Gated Channel Subunit Alpha1C
  • Anti-Ca<sub>V</sub>1.2 (CACNA1C) Antibody
    KO Validate'
    Anti-CaV1.2 (CACNA1C) Antibody
    A Rabbit Polyclonal Antibody to CaV1.2 (CACNA1C) Channel
    • Product Code: ACC-003
    • Short Description: A Rabbit Polyclonal Antibody to CaV1.2 (CACNA1C) Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: Voltage-dependent L-type calcium channel subunit α1C
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