Antagonists

Histamine Receptors

Antagonists

Histamine (2-[4-imidazole]ethylamine) is a low-molecular-weight amine synthesized from L-histidine. It is produced by various cells throughout the body, including central nervous system neurons, gastric mucosa parietal cells, mast cells, basophils and lymphocytes. Histamine is a major biological mediator whose functions include, among many others, regulation of vascular smooth muscle, immune regulation, regulation of sleep-wake cycles and regulation of gastric acid secretion.
The biological effects of histamine are mediated through four receptors (H1– H4 Histamine receptors) all of which belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily.

Displaying 1 to 4 products (out of 4 products)
  • Clobenpropit dihydrobromide

    A Potent and Selective Antagonist of Histamine H3 Receptors, An Antagonist of NMDA Receptors

    Cat # C-345
    Source Synthetic
    MW 470.65
    Target Histamine H3, Histamine H4, NMDA receptors
  • Mirtazapine

    An Antagonist of 5-HT2, 5-HT3, Histamine H1 Receptors and α2-Adrenoceptor

    Cat # M-130
    Source Synthetic
    MW 265.4
    Target 5-HT3, 5-HT2, Histamine H1, α2 adrenergic receptors
  • Orphenadrine citrate salt

    An Antagonist of Muscarinic and NMDA Receptors and Voltage-Gated Na+ Channels

    Cat # O-100
    Source Synthetic
    MW 461.5
    Target Muscarinic, H1 histamine, NMDA receptors, NaV Na+ channels
  • Orphenadrine hydrochloride

    An Antagonist of Muscarinic and NMDA Receptors and Voltage-Gated Na+ Channels

    Cat # O-101
    Source Synthetic
    MW 305.8
    Target Muscarinic, H1 histamine, NMDA receptors, NaV Na+ channels

* See product page

Displaying 1 to 4 products (out of 4 products)