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Apelin Receptor


The apelin receptor (APJ) is a member of the G protein-coupled receptor gene family, encoded by the APLNR gene. The apelin receptor and its endogenous ligand, apelin, have been suggested to act as key mediators of physiological responses to multiple homeostatic actions, including cardiovascular control, water balance, hypothalamic–pituitary–adrenal (HPA) axis regulation and metabolic homeostasis.

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