Antibodies

Glial-Derived Neurotrophic Factor (GDNF) Family Receptors

Antibodies

The GDNF family ligands (GFLs) belong to the super family of the TGF-β. They belong to the group of cystine-knot protein and function as homodimers. This family includes glial cell line-derived neurotrophic factor (GDNF), artemin (ARTN), Neurturin (NRTN) and persephin (PSPN). These factors are heavily involved in the development and function of the nervous system (both central and peripheral). In general GFLs all signal through a signal through the receptor tyrosine kinase Ret. Their specificity is implemented by different GDNF family receptor α (GFRα), which act as co-receptors. These extracellular proteins are bound to the plasma membrane via a glycosyl phosphatidyl inositol (GPI) anchor. GFRα1-4 are responsible for the binding of GDNF, NRTN, ARTN, and PSPN respectively and the subsequent activation of Ret.

Displaying 1 to 4 products (out of 4 products)
  • Anti-GFR alpha 1 (extracellular) Antibody

    A Rabbit Polyclonal Antibody to GDNF Family Receptor α1

    Cat # ANT-021
    Type Polyclonal
    Source Rabbit
    Applications ic, ih, lci, wb, ifc*, ip*
    Reactivity h, m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-GFR alpha 3 (extracellular) Antibody

    A Rabbit Polyclonal Antibody to GDNF Family Receptor α3

    Cat # ANT-023
    Type Polyclonal
    Source Rabbit
    Applications wb, ic*, ifc*, ih*, ip*, lci*
    Reactivity m, r, h*
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-GFR alpha 4 (extracellular) Antibody

    A Rabbit Polyclonal Antibody to GDNF Family Receptor α4

    Cat # ANT-024
    Type Polyclonal
    Source Rabbit
    Applications ic, ih, lci, wb, ifc*, ip*
    Reactivity m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-Ret (extracellular) Antibody

    A Rabbit Polyclonal Antibody to Ret Receptor 

    Cat # ANT-025
    Type Polyclonal
    Source Rabbit
    Applications ic, ifc, ih, lci, wb, ip*
    Reactivity h, m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.

* See product page

Displaying 1 to 4 products (out of 4 products)