Antibodies to Kainate Receptors

Kainate Receptors

Antibodies to Kainate Receptors

The kainate receptor subfamily consists of five members that have been further subdivided into two classes based upon structural homology and functional characteristics. GluR5, GluR6, and GluR7 receptor subunits share a high degree of homology and are able to form functional channels when expressed in heterologous systems. The KA-1 and KA-2 receptors are unable to form functional channels on their own, but when coexpressed with GluR5-7 receptor subunits, they form channels with high affinity for kainate. Like AMPA receptors, the functional unit of endogenous kainate receptors is believed to be a tetramer, which can be either homomeric or heteromeric. Kainate receptors GluR5 and GluR6 (but not GluR7, KA-1, or KA-2) can undergo RNA editing; as in the AMPA receptor GluR2, a glutamine (Q) residue in the channel pore is edited to encode arginine (R) in the mature protein. Substitution of Q with R modulates the properties of the channel, producing channels with reduced single channel conductance and lower permeability to Ca2+.

Displaying 1 to 7 products (out of 7 products)
  • Anti-Kainate Receptor GluK1 (extracellular) Antibody

    A Rabbit Polyclonal Antibody to Kainate Receptor GluK1

    Cat # AGC-008
    Type Polyclonal
    Source Rabbit
    Applications ic, ih, lci, wb, ifc*, ip*
    Reactivity r, h*, m*
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-Kainate Receptor GluK2 Antibody

    A Rabbit Polyclonal Antibody to Kainate Receptor GluK2

    Cat # AGC-009
    Type Polyclonal
    Source Rabbit
    Applications ic, wb, ifc*, ih*, ip*
    Reactivity h, m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-Kainate Receptor GluK3 (extracellular) Antibody

    A Rabbit Polyclonal Antibody to Kainate Receptor GluK3

    Cat # AGC-040
    Type Polyclonal
    Source Rabbit
    Applications ih, wb, ic*, ifc*, ip*, lci*
    Reactivity h, m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-Kainate Receptor GluK4 (extracellular) Antibody

    A Rabbit Polyclonal Antibody to Kainate Receptor GluK4

    Cat # AGC-041
    Type Polyclonal
    Source Rabbit
    Applications ic, ih, wb, fc*, ifc*, ip*, lci*
    Reactivity h, m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-Kainate Receptor GluK5 (extracellular) Antibody

    A Rabbit Polyclonal Antibody to Kainate Receptor GluK5

    Cat # AGC-042
    Type Polyclonal
    Source Rabbit
    Applications ic, ih, wb, ifc*, ip*, lci*
    Reactivity h, m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • iGluR Antibodies for Pain Research Explorer Kit

    A Screening Package of iGluR Antibodies for Pain Research Economically Priced

    Cat # AK-395
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Kainate Receptor Antibody Explorer Kit

    A Screening Package of Kainate Receptor Antibodies Economically Priced

    Cat # AK-555
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.

* See product page

Displaying 1 to 7 products (out of 7 products)