Blockers

L-Type (CaV1) Channels

Blockers

L-type Ca2+ channels include four different isoforms of the α1 pore-forming subunit: CaV1.1, CaV1.2, CaV1.3 and CaV1.4. Their expression is detected in muscle, heart, retina and neurons where they play important roles in muscle contraction, hormone secretion, neuronal excitability and gene expression.

Displaying 1 to 20 (out of 27 products)
  • Amitriptyline hydrochloride

    A Blocker of L-type CaV Channels, an Antagonist of 5-HT2 Serotonin Receptors, and an Agonist of α-Adrenoceptors

    Cat # A-155
    Source Synthetic
    MW 313.86
    Target L-type Ca2+ channels, α-adrenergic receptors, 5-HT2 serotonin receptors
    • Lyophilized Powder
  • Amlodipine

    A Potent Blocker of L-type and T-type CaV Channels

    Cat # A-110
    Source Synthetic
    MW 408.9
    Target L-type and T-type Ca2+ channels
    • Lyophilized Powder
  • Amlodipine besylate

    A Potent Blocker of L-Type and T-Type CaV Channels

    Cat # A-120
    Source Synthetic
    MW 567.1
    Target L-type and T-type Ca2+ channels
    • Lyophilized Powder
  • Azelnidipine

    A Potent Blocker of L-type CaV Channels

    Cat # A-135
    Source Synthetic
    MW 582.65
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • (R)(+)-Bay K8644

    A Blocker of L-Type CaChannels

    Cat # B-352
    Source Synthetic
    MW 356.3
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Benidipine hydrochloride

    A Dihydropyridine Blocker of Voltage-Gated Ca2+ Channels

    Cat # B-120
    Source Synthetic
    MW 542
    Target CaV3, CaV1 Ca2+ channels
    • Lyophilized Powder
  • Calcicludine

    A Blocker of Neuronal L-Type CaV Channels

    Cat # SPC-650
    MW 6979 Da.
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Calciseptine

    A Specific Blocker of L-Type CaV Channels

    Cat # SPC-500
    MW 7036 Da.
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Celecoxib

    A Blocker of CaV1 Channels, a COX-2 Inhibitor and an Opener of KCNQ Channels 

    Cat # C-190
    Source Synthetic
    MW 381.4
    Target L-type Ca2+ and KCNQ channels
    • Lyophilized Powder
  • Cilnidipine

    A Blocker of L- and N-Type CaV channels 

    Cat # C-135
    Source Synthetic
    MW 492.5
    Target L- and N-type Ca2+ channels
    • Lyophilized Powder
  • Felodipine

    A Potent and Selective Blocker of L-Type CaV Channels

    Cat # F-105
    Source Synthetic
    MW 384.25
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Flavoxate hydrochloride

    A Blocker of Voltage-Gated L-Type Ca2+ Channels

    Cat # F-140
    Source Synthetic
    MW 427.9
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Flunarizine dihydrochloride

    A Potent Blocker of L-type and T-type CaV Channels

    Cat # F-110
    Source Synthetic
    MW 477.4
    Target L-type and T-type Ca2+ channels
    • Lyophilized Powder
  • FS-2

    A Blocker of L-Type CaV Channels

    Cat # F-700
    MW 7026 Da.
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Isradipine

    A Potent Blocker of L-Type (both CaV1.2 and CaV1.3) Ca+ Channels

    Cat # I-100
    Source Synthetic
    MW 371.4
    Target CaV1.2, CaV1.3 Ca2+ channels
    • Lyophilized Powder
  • L-651,582

    An Effective Blocker of L-Type CaV Channels

    Cat # L-110
    Source Synthetic
    MW 424.7
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Lercanidipine hydrochloride

    A Potent and Selective Blocker of L-type CaV Channels

    Cat # L-115
    Source Synthetic
    MW 648.2
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Lomerizine dihydrochloride

    A Blocker of L-Type Voltage-Gated Ca2+ Channels

    Cat # L-125
    Source Synthetic
    MW 541.5
    Target L-type Ca2+ channels
    • Lyophilized Powder
  • Loperamide hydrochloride

    An Antagonist of L-type and T-type CaV Channels, HCN Channels, NMDA Receptors and an Agonist of μ-Opioid Receptors

    Cat # L-100
    Source Synthetic
    MW 513.5
    Target L-type, T-type Ca2+, HCN channels, NMDA, μ-opioid receptors
    • Lyophilized Powder
  • (±)-Naringenin

    A Blocker of Vascular L-type CaV Channels

    Cat # N-110
    Source Synthetic
    MW 272.25
    Target L-type Ca2+ channels
    • Lyophilized Powder

* See product page

Displaying 1 to 20 (out of 27 products)