Blockers

TRPM Channels

Blockers

The mammalian melastatin-related transient receptor potential (TRPM) is a subfamily of the TRP family. The family was named after the first member, melastatin (TRPM1), whose gene was identified in metastatic and benign melanomas. The TRPM proteins share structural homology with other members of the TRP superfamily channels; six putative transmembrane domains, and cytoplasmic N-terminus and C-terminus. However, due to their long N-terminus and C-terminus they were also named the long TRP channel family.The TRPM family consists of eight members designated as TRPM1-8 that can be further divided into four pairs: TRPM1 and TRPM3; TRPM2 and TRPM8; TRPM4 and TRPM5; and TRPM6 and TRPM7.

Displaying 1 to 17 products (out of 17 products)
  • AMG2850

    A Potent and Selective Blocker of TRPM8 Channels

    Cat # A-340
    Source Synthetic
    MW 417.35
    Target TRPM8 channel
  • AMG-9090

    A Blocker of TRPA1, TRPV1 and TRPM8 Channels

    Cat # A-300
    Source Synthetic
    MW 395.12
    Target TRPA1, TRPM8, TRPV1 channels
  • AMTB hydrochloride

    A Blocker of TRPM8 Channels

    Cat # A-305
    Source Synthetic
    MW 430.99
    Target TRPM8 channel
  • BCTC

    A Potent Antagonist of TRPV1 and TRPM8 Channels

    Cat # B-110
    Source Synthetic
    MW 372.9
    Target TRPV1 and TRPM8 channels
  • Cannabichromene

    An Activator of TRPA1 Channels and an Antagonist of Cannabinoid Receptor 1 and TRPM8 Channels

    Cat # C-315
    Source Synthetic
    MW 314.5
    Target TRPA1, TRPM8 channels, Cannabinoid Receptor 1
  • CyPPA

    A Selective and Potent Activator of KCa2.2 and KCa2.3 Channels and a Blocker of TRPM7 Channels

    Cat # C-110
    Source Synthetic
    MW 285.4
    Target KCa2.2, KCa2.3, TRPM7 channels
  • M8-B hydrochloride

    A Potent and Selective Blocker of TRPM8 Channel

    Cat # M-220
    Source Synthetic
    MW 432.96
    Target TRPM8 channel
  • NS8593

    A Blocker of KCa2 and TRPM7 Channels

    Cat # N-196
    Source Synthetic
    MW 263.3
    Target SK K+ channels, TRPM7
  • NS8593 hydrochloride

    A Blocker of KCa2 and TRPM7 Channels

    Cat # N-195
    Source Synthetic
    MW 299.79
    Target SK K+ channels, TRPM7
  • Ononetin

    A Potent TRPM3 Channel Blocker and a TRPA1 Channel Activator

    Cat # O-135
    Source Synthetic
    MW 258.27
    Target TRPM3, TRPA1 channels
  • Rosiglitazone

    A Blocker of Kir6.1, KV4.3, TRPM3 and an Activator of TRPC5 and PPAR Ligand

    Cat # R-125
    Source Synthetic
    MW 357.43
    Target KV4, Kir6.1, TRPM3, TRPC5 channels
  • RQ 00203078

    A Potent and Selective Blocker of TRPM8 Channels

    Cat # R-170
    Source Synthetic
    MW 554.84
    Target TRPM8 channel
  • SKA-31

    A Potent Activator of KCa3.1 and KCa2 Channels and a Blocker of TRPM7 Channel 

    Cat # S-120
    Source Synthetic
    MW 200.2
    Target KCa2, KCa3.1, TRPM7 channels
  • TC-I 2014

    A Potent and Selective Blocker of TRPM8 Channels

    Cat # T-200
    Source Synthetic
    MW 467.41
    Target TRPM8 channel
  • TRPM8 Channel Blocker Explorer Kit

    A Screening Package of TRPM8 Channel Blockers Economically Priced

    Cat # EK-151
    • Lyophilized Powder
    • Bioassay Tested
    • Shipped at Room Temp.
  • TRPM8 Channel Modulator Explorer Kit

    A Screening Package of TRPM8 Channel Modulators Economically Priced

    Cat # EK-152
    • Lyophilized Powder
    • Bioassay Tested
    • Shipped at Room Temp.
  • TRPM8 Channel Basic Research Pack

    All You Need for TRPM8 Channel Research

    Cat # ESB-301
    • Lyophilized Powder
    • Antigen Incl.
    • Bioassay Tested
    • Shipped at Room Temp.

* See product page

Displaying 1 to 17 products (out of 17 products)