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Antibodies raised in guinea pig can be used with antibodies raised in mouse, rabbit, goat, etc. in complex immunostaining or immunoprecipitation protocols.

The transport of Glu into the cells by the EAAT transporters is coupled to the Na⁺ and K⁺ electrochemical gradient as a driving force. Hence, the uptake of Glu is dependent on the co-transport of three Na⁺ and one H⁺ ions, and the counter transport of one K⁺ ion.
In addition, to the well documented Glu uptake, the EAAT transporters show a Glu-independent Cl^– conductance. The physiological significance of the Cl^– current through the EAATs is currently unknown.