Inhibitors

Monoamine Transporters

Inhibitors

Many physiological, endocrine and behavioral functions are determined and regulated by monoamine signaling. Many brain disorders such as depression, drug abuse, schizophrenia, attention deficit hyperactivity disorder (ADHD) are caused by the malfunction of monoaminergic transmission. The intensity of monoaminergic signaling is determined by the availability of the monoamine, which is in turn determined in part by its uptake from the extracellular milieu via monoamine transporters. These transporters include DAT, SERT, and NET, responsible for uptaking dopamine, serotonin (5-HT) and noradrenaline respectively, and recycling them back for release. DAT, SERT and NET are members of the Na+/Cl dependent membrane transporter family which also includes other members.

Displaying 1 to 4 products (out of 4 products)
  • Citalopram

    A Blocker of KV2 Channels and an Inhibitor of 5HT Uptake

    Cat # C-195
    Source Synthetic
    MW 324.4
    Target KV2 K+ channels
  • Citalopram hydrobromide

    A Blocker of KV2 Channels and an Inhibitor of 5-HT Uptake

    Cat # C-185
    Source Synthetic
    MW 405.31
    Target KV2 K+ channels
  • (S)-Duloxetine hydrochloride

    A Blocker of KV4.3 and an Inhibitor of 5-HT and Norepinephrine Re-Uptake

    Cat # D-170
    Source Synthetic
    MW 333.9
    Target KV4.3 channels
  • MCI-225

    A Potent Antagonist of 5-HT3 Channels and a Selective Noradrenaline Reuptake Inhibitor

    Cat # M-190
    Source Synthetic
    MW 328.4
    Target 5-HT3A receptor, NET transporter

* See product page

Displaying 1 to 4 products (out of 4 products)