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Live Cell Imaging Products

Extracellular antibodies are ideal research tools for cell-surface proteins.

 

No permeabilization/fixation because using extracellular antibodies allows you to work with live cells!

 

Benefits of live cell imaging:
Monitor cell movement
Study protein transport across the cell
Investigate protein internalization

Store-Operated Ca2+ Channels

Changes in the cytoplasm free Ca2+ concentration [Ca2+]in regulate a large number of relevant physiological processes and have a major impact on cell development and function. The identification of STIM, the endoplasmic reticulum (ER) Ca2+ sensor, and Orai, a key subunit of the Ca2+ release-activated Ca2+ (CRAC) channel pore, have provided the tools to illuminate the mechanisms of CRAC channel regulation, that play an important role in modulation of the free Ca2+ concentration in non-excitable cells. Store-operated Ca2+ entry (SOCE) is a common and ubiquitous mechanism for regulating Ca2+ influx into cells and is widely expressed in most tissues.

  • Mouse Anti-Human Orai1 (extracellular) Antibody

    A Mouse Monoclonal Antibody to Human Orai1 Channel

    Cat # ALM-025
    Type Monoclonal
    Host Mouse
    Applications icc, if, ifc, lci, wb, ihc*
    Reactivity h
  • Anti-Orai1 (extracellular) Antibody

    A Rabbit Polyclonal Antibody to Orai1 Channel

    Cat # ACC-062
    Type Polyclonal
    Host Rabbit
    Applications icc, if, ifc, ihc, lci, wb, ip*
    Reactivity m, r
    • KO Validated
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