Kᵢᵣ1.1/ROMK1

Shop Popular Products

Product Categories

No categories available

FAQs

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Curabitur quis risus id enim vehicula interdum et ac sem.

  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

8 Results
  • Tertiapin-Q-ATTO Fluor-633
    Bioassay Tested
    Tertiapin-Q-ATTO Fluor-633
    A fluorescent probe for imaging and sensitive detection of Kir1.1 and GIRK potassium channels
    • Product Code: STT-170-FR
    • Short Description: A fluorescent probe for imaging and sensitive detection of Kir1.1 and GIRK potassium channels
    • Label: ATTO 633
    • Applications: Electrophysiology, Fluorescence staining, Live cell imaging, Immunofluorescence
    • MW: 3159.6 Da
  • Tertiapin-Q-ATTO Fluor-488
    Bioassay Tested
    Tertiapin-Q-ATTO Fluor-488
    A fluorescent probe for imaging and sensitive detection of Kir1.1 and GIRK potassium channels
    • Product Code: STT-170-AG
    • Short Description: A fluorescent probe for imaging and sensitive detection of Kir1.1 and GIRK potassium channels
    • Label: ATTO 488
    • Applications: Electrophysiology, Direct flow cytometry, Live cell imaging, Immunofluorescence
    • MW: 3195.5 Da
  • Tertiapin
    Bioassay Tested
    Tertiapin
    A potent blocker of Kir1.1, GIRK, and KCa1.1 (BK) potassium channels
    • Product Code: STT-250
    • Short Description: A potent blocker of Kir1.1, GIRK, and KCa1.1 (BK) potassium channels
    • Applications: Electrophysiology
    • CAS No.: 58694-52-3
    • MW: 2455 Da
  • Tertiapin-LQ
    Bioassay Tested
    Tertiapin-LQ
    A potent and highly selective blocker of Kir1.1 (ROMK) K+ channels
    • Product Code: STT-220
    • Short Description: A potent and highly selective blocker of Kir1.1 (ROMK) K+ channels
    • Applications: Electrophysiology
    • MW: 2428 Da
  • Tertiapin-RQ
    Bioassay Tested
    Tertiapin-RQ
    A blocker of Kir1.1, Kir3.1 and Kir3.4 K+ channels
    • Product Code: STT-180
    • Short Description: A blocker of Kir1.1, Kir3.1 and Kir3.4 K+ channels
    • Applications: Electrophysiology
    • MW: 2496 Da
  • Tertiapin-Q
    Bioassay Tested
    Tertiapin-Q
    A potent blocker of Kir1.1 and GIRK potassium channels
    • Product Code: STT-170
    • Short Description: A potent blocker of Kir1.1 and GIRK potassium channels
    • Applications: Electrophysiology
    • CAS No.: 910044-56-3
    • MW: 2452 Da
  • Lq2
    Bioassay Tested
    Lq2
    A potent blocker of Kir1.1 (ROMK1) channels, with lower affinity on KCa1.1 (BK) channels
    • Product Code: RTL-550
    • Short Description: A potent blocker of Kir1.1 (ROMK1) channels, with lower affinity on KCa1.1 (BK) channels
    • Applications: Electrophysiology
    • MW: 4353 Da
  • δ-Dendrotoxin
    Bioassay Tested
    δ-Dendrotoxin
    A potent and specific blocker of KV1.1 channels, with lower potency for KV1.6 and Kir1.1 (ROMK1) channels
    • Product Code: D-380
    • Short Description: A potent and specific blocker of KV1.1 channels, with lower potency for KV1.6 and Kir1.1 (ROMK1) channels
    • Applications: Electrophysiology
    • MW: 6568 Da
Loading...

Have questions about our products?

Step-by-Step Protocols