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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.
  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

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790 Results
  • Charybdotoxin
    A potent broad-spectrum blocker of K+ channels, including KV1.2, KV1.3, KV1.6, KCa1.1 and KCa3.1 channels
    • Product Code: STC-325
    • Short Description: A potent broad-spectrum blocker of K+ channels, including KV1.2, KV1.3, KV1.6, KCa1.1 and KCa3.1 channels
    • Applications: Electrophysiology
    • CAS No.: 95751-30-7
    • MW: 4296 Da
  • Chlormethiazole hydrochloride
    A Positive Modulator of GABA(A) and Glycine Receptors
    • Product Code: C-360
    • Short Description: A Positive Modulator of GABA(A) and Glycine Receptors
    • CAS No.: 6001-74-7
    • MW: 198.11
  • Chlorotoxin
    A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Product Code: STC-460
    • Short Description: A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Applications: Cell-Based Assays, Electrophysiology, Calcium imaging assay
    • CAS No.: 163515-35-3
    • MW: 3995.8 Da
  • Chlorotoxin
    A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Product Code: RTC-450
    • Short Description: A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Applications: Cell-Based Assays, Electrophysiology, Calcium imaging assay
    • CAS No.: 163515-35-3
    • MW: 3996.7 Da
  • Cilnidipine
    A Blocker of L- and N-Type CaV Channels
    • Product Code: C-135
    • Short Description: A Blocker of L- and N-Type CaV Channels
    • CAS No.: 132203-70-4
    • MW: 492.5
  • cis-ACBD
    An Agonist of NMDA Receptors
    • Product Code: A-281
    • Short Description: An Agonist of NMDA Receptors
    • CAS No.: 73550-55-7
    • MW: 159.14
  • Cl-HIBO
    An Agonist of AMPA Receptors
    • Product Code: C-355
    • Short Description: An Agonist of AMPA Receptors
    • CAS No.: 909400-43-7
    • MW: 206.58
  • CLIC5 Blocking Peptide
    A Blocking Peptide for Anti-CLIC5 Antibody
    • Product Code: BLP-CL025
    • Short Description: A Blocking Peptide for Anti-CLIC5 Antibody
    • Applications: Western blot, Immunohistochemistry
    • Target: CLIC5
  • CMPDA
    An AMPA Receptor Positive Allosteric Modulator
    • Product Code: C-215
    • Short Description: An AMPA Receptor Positive Allosteric Modulator
    • CAS No.: 380607-77-2
    • MW: 376.1
  • Cn2 Toxin
    A potent and selective activator of NaV1.6 channels
    • Product Code: STC-060
    • Short Description: A potent and selective activator of NaV1.6 channels
    • Applications: Electrophysiology
    • MW: 7588.6 Da
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