Agonists

Nicotinic Acetylcholine Receptors

Agonists

nAChRs are pentameric complexes made up of combinations of a number of different nAChR subunits, which can be classified as α subunits, containing two cysteine residues at positions analogous to Cys192 and Cys193, and non-alpha subunits (‘structural’ subunits), which can be defined as β subunits when they are expressed in the vertebrate nervous system. There are nine α subunits (α2–α10) and three β subunits (β2, β3, and β4) in the CNS. Nicotinic receptors are assembled as combinations of α (2-6) and and β (2-4) subunits.

Displaying 1 to 13 products (out of 13 products)
  • 1,1-Dimethyl-4-phenylpiperazinium iodide

    An Agonist of nAChR

    Cat # D-125
    Source Synthetic
    MW 318.2
    Target nAChR
    • Lyophilized Powder
  • α-Conotoxin MrIC

    An Antagonist and Partial Agonist of α7 nAChR

    Cat # STC-320
    Source Synthetic peptide
    MW 1839.09 Da.
    Target α7 nAChR
    • Lyophilized Powder
  • (-)-Cytisine

    A nAChR Agonist and a Partial Agonist of β2 Subunit

    Cat # C-130
    Source Synthetic
    MW 190.2
    Target nAChR
    • Lyophilized Powder
  • DMAB-anabaseine dihydrochloride

    Antagonist or Partial Agonist of nAChR

    Cat # D-110
    Source Synthetic
    MW 364.3
    Target nAChR
    • Lyophilized Powder
  • Ivermectin

    A Positive Allosteric Modulator of α7 nAChR and of human P2X4 Receptor

    Cat # I-110
    Source Synthetic
    MW 875.09
    Target α7 nAChR, P2X, GABA(A)R
    • Lyophilized Powder
  • (-)-Nicotine ditartrate

    An Agonist of nAChR

    Cat # N-175
    Source Synthetic
    MW 462.4
    Target nAChR
    • Lyophilized Powder
  • PNU-120596

    A Potent and Selective Positive Allosteric Modulator of α7 nAChR

    Cat # P-350
    Source Synthetic
    MW 311.72
    Target α7 nAChR
    • Lyophilized Powder
  • PNU 282987

    Selective Agonist of α7 nAChR

    Cat # P-110
    Source Synthetic
    MW 264.75
    Target α7 nAChR
    • Lyophilized Powder
  • RJR 2403 oxalate

    An Agonist of α4/β2 nAChRs

    Cat # R-115
    Source Synthetic
    MW 252.3
    Target α4/β2 nAChRs
    • Lyophilized Powder
  • Varenicline tartrate

    A Partial Agonist of α4/β2 nAChR and a Full Agonist of α7 nAChR

    Cat # V-105
    Source Synthetic
    MW 361.3
    Target α4/β2, α7 nAChR
    • Lyophilized Powder
  • Ion Channel Activators for Pain Research Explorer Kit

    A Screening Package of Ion Channel Activators for Pain Research Economically Priced

    Cat # EK-395
    • Lyophilized Powder
  • nAChR Agonist Explorer Kit

    A Screening Package of nAChR Activators Economically Priced

    Cat # EK-204
    • Lyophilized Powder
  • nAChR Modulator Explorer Kit

    A Screening Package of nAChR Modulators Economically Priced

    Cat # EK-202
    • Lyophilized Powder

* See product page

Displaying 1 to 13 products (out of 13 products)