NOW you can conduct flow cytometry using live cells in ONE single step.
These novel antibodies save you valuable time and resources, while empowering your research results.
✓ Developed for flow cytometry (FACS) ✓ Tested with appropriate isotype control ✓ No need for secondary antibodies ✓ Conjugated to “extracellular” antibodies ✓ Cell-surface detection of proteins ✓ Permeabilization & cell fixation not required ✓ Time saving
Within our antibody portfolio, we gladly take on special requests for customized antibody labeling/conjugation.
Anoctamin (ANO, or TMEM16) is a family of membrane proteins which includes 10 members. This family is named so because these channels selective to ANions and have eight (OCT) transmembrane domains. Also, these channels are subject to glycosylation in their extracellular loops and have both intracellular N- and C-termini. Members of this family are expressed in a broad range of different organisms ranging from mammals, flies, worms, plants as well as yeast. Alternative splicing is known to affect these channels and regarding their oligomerization state, homedimerization has been observed although when heterologously expressed, these channels may hetero oligomerize.