Antibodies

Multidrug and Toxin Extrusion Transporters

Antibodies

MATE1 (SLC47A1) and MATE2 (SLC47A2) are multidrug and toxin extrusion transporter 1 and 2 function as cationic pumps in the kidneys, liver, and intestine. Both MATEs excrete molecules with a positive net-charge from renal tubular epithelial cells in the kidney (where they are co-expressed with organic anion- and cation-transporters; OATs and OCTs), and into the urine. In the liver, MATE1, but not MATE2, regulates the transportation of tetraethylammonium (TEA) and 1-methyl-4-phenylpyridinium (MPP) – again, by cation-powered pumps.

Displaying 1 to 2 products (out of 2 products)
  • Anti-SLC47A1 Antibody

    A Rabbit Polyclonal Antibody to SLC47A1

    Cat # ANT-131
    Type Polyclonal
    Source Rabbit
    Applications wb, ic*, ifc*, ih*, ip*
    Reactivity m, r
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.
  • Anti-SLC47A2 Antibody

    A Rabbit Polyclonal Antibody to SLC47A2

    Cat # ANT-132
    Type Polyclonal
    Source Rabbit
    Applications wb, ic*, ifc*, ih*, ip*
    Reactivity m, r*
    • Lyophilized Powder
    • Antigen Incl.
    • Shipped at Room Temp.

* See product page

Displaying 1 to 2 products (out of 2 products)