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Calcium Sensing Receptor

The Calcium-Sensing Receptor (CaSR) is a member of the G-protein-coupled receptor (GPCR) superfamily. As its primary role, the CaSR is a key player in calcium homeostasis and is expressed in tissues involved in calcium metabolism, such as parathyroid cells and kidney. CaSR regulates cellular processes such as proliferation, apoptosis, and differentiation under both normal and pathologic conditions.