Ca2+ ATPases


PMCA belongs to a family of P-type primary ion transport ATPases, and is expressed in a variety of tissues, including the brain.
In mammals three genes encode three SERCA pumps. Each transcript undergoes tissue-dependent alternative splicing. SERCA1a and 1b are expressed in adult and neonatal skeletal muscle respectively. SERCA2a is also expressed in skeletal muscle, while SERCA2b is ubiquitously expressed. SERCA3 is expressed in a limited number of non-muscle cells. Although all SERCAs are regulated, SERCA2b undergoes extensive regulation at the protein level, such as protein-protein interaction, phosphorylation and glycosylation.

Displaying 1 to 9 products (out of 9 products)
  • Chelerythrine chloride

    An Inhibitor of Protein Kinase C, SERCA Pump, and P2X7 Receptor

    Cat # C-400
    Source Natural
    MW 383.84
    Target PKC, SERCA pumps, P2X7 receptor
  • Cyclopiazonic Acid

    A Potent Inhibitor of Intracellular Ca2+-ATPase Pump

    Cat # C-750
    Source Natural
    MW 336.4
    Target SERCA pump
  • NS-1619

    Selective and Potent Enhancer of KCa1.1 Channels and an Inhibitor of SERCA Pumps

    Cat # N-105
    Source Synthetic
    MW 362.2
    Target KCa1.1 K+ channels, SERCA pumps
  • Ochratoxin A

    A Potent Modulator of Ca2+ ATPase Pump

    Cat # O-400
    Source Natural
    MW 403.8
    Target SERCA pump
  • Paxilline

    A Mycotoxin Blocker of KCa1.1 (BK) Channels and SERCA Pumps

    Cat # P-450
    Source Natural
    MW 435.6
    Target KCa K+ channels, SERCA pump
  • tBuBHQ

    A Potent Inhibitor of Sarcolasmic Reticulum Ca2+ ATPase

    Cat # T-220
    Source Synthetic
    MW 222.33
    Target SERCA
  • Thapsigargin

    A Potent and Cell-Permeable Inhibitor of SERCA Pump Ca2+-ATPase/an Intracellular Ca2+ Mobilizer

    Cat # T-650
    Source Natural
    MW 650.7
    Target SERCA
  • Thapsigargin Epoxide

    A Nonactive Analogue of Thapsigargin

    Cat # T-670
    Source Natural
    MW 632.75
    Target SERCA
  • SERCA Pump Inhibitor Explorer Kit

    A Screening Package of SERCA Pump Inhibitors Economically Priced

    Cat # EK-365

* See product page

Displaying 1 to 9 products (out of 9 products)