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Pannexin Family

Pannexins (Pannexin 1, Pannexin 2 and Pannexin 3) also belong to the superfamily of gap junction proteins. Pannexin 1 (PANX1) is ubiquitously expressed, Pannexin 2 (PANX2) is specifically expressed in the human brain and widespread in rodents and Pannexin 3 (PANX3) is also detected in the brain.