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Live Cell Imaging Products

Extracellular antibodies are ideal research tools for cell-surface proteins.

 

No permeabilization/fixation because using extracellular antibodies allows you to work with live cells!

 

Benefits of live cell imaging:
Monitor cell movement
Study protein transport across the cell
Investigate protein internalization

Sphingosine 1-Phosphate Receptors

Sphingosine 1-phosphate (S1P) is an active byproduct of sphingomyelin metabolism. Upon secretion, it circulates in the blood via its binding to high-density lipoproteins and albumin. When S1P reaches its target cell it could activate 5 different high affinity receptors belonging to the G-protein coupled receptor superfamily: Sphingosine 1-phosphate receptors, termed S1PR1-5. Stimulation of S1PR receptors triggers a cascade of signaling events depending on the receptor and on the G-protein it couples. Through the different signaling pathways these receptors activate, S1PR receptors are implicated in adherens junction assembly, cytoskeletal changes, cell migration, proliferation and apoptosis.

  • Anti-S1PR1 (EDG1) (extracellular) Antibody

    A Rabbit Polyclonal Antibody to Sphingosine 1-Phosphate Receptor 1

    Cat # ASR-011
    Type Polyclonal
    Host Rabbit
    Applications icc, if, ifc, ihc, lci, wb, ip*
    Reactivity h, m, r
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