JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Ion Channels

Ion Channels

Engineered venom-derived peptide toxins designed for high-specificity ion channel research and reproducible experimental performance.

Our toxins are developed in-house using controlled synthesis, folding, and multistep purification workflows that eliminate non-specific components found in crude venom. Each peptide is validated by HPLC, mass spectrometry, and functional bioassays, for lot-to-lot consistency and reliable performance. Available in synthetic, recombinant, native, and optionally fluorophore-conjugated formats. These reagents enable precise functional electrophysiology, imaging, and live-cell studies across neuronal systems.

Shop Popular Products

Product Categories

No categories available

FAQs

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Curabitur quis risus id enim vehicula interdum et ac sem.

The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.
- If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
  • Heat the samples at 70°C for 10 min.
  • Increase the transfer time.
- If the band’s MW is above the expected MW, it could be due to post-translational modifications.
- In either event, you should use a blocking peptide as a negative control.
Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.
1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.
Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.
FAQ 3FAQ 3FAQ 3FAQ 3

Filtered by:

Naᵥ1.9

Clear

4 Results

Powered by Bioz See more details on Bioz

Tf2 Toxin

An activator/gating modifier of NaV1.3 and NaV1.9 channels
- Product Code: STT-050
- Short Description: An activator/gating modifier of Na_V1.3 and Na_V1.9 channels
- Applications: Electrophysiology
- MW: 6954 Da
Powered by Bioz See more details on Bioz

Myrmicitoxin1-Pm2a

A potent gating modifier of sensory neuron NaV1.6, NaV1.7, NaV1.8, and NaV1.9 channels
- Product Code: STP-040
- Applications: Electrophysiology
- MW: 3189.9 Da
Powered by Bioz See more details on Bioz

Jingzhaotoxin-V

A highly potent inhibitor of NaV1.7 channels, with weaker activity on other NaV subtypes and KV4.2/4.3 channels
- Product Code: STJ-050
- Applications: Electrophysiology
- MW: 3605.4 Da
Powered by Bioz See more details on Bioz

Heteropodatoxin-1

An activator of NaV1.9 and an inhibitor of KV4.2 and NaV1.7
- Product Code: STH-320
- Short Description: An activator of Na_V1.9 and an inhibitor of K_V4.2 and Na_V1.7
- Applications: Electrophysiology
- MW: 3910.4 Da

Loading...

Have questions about our products?

Step-by-Step Protocols