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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

Category: Galanin Receptors
Category: G Protein-Coupled Receptors (GPCRs)
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38 Results
  • α-Conotoxin Vc1.1
    Bioassay Tested
    α-Conotoxin Vc1.1
    A potent antagonist of α9α10 nAChRs and agonist of GABA(B) receptors
    • Product Code: STV-500
    • Short Description: A potent antagonist of α9α10 nAChRs and agonist of GABA(B) receptors
    • Applications: Electrophysiology
    • CAS No.: 740980-24-9
    • MW: 1807 Da
  • Muscarinic Toxin 7
    Bioassay Tested
    Muscarinic Toxin 7
    A negative allosteric modulator (NAM) of the M1 Muscarinic Receptor
    • Product Code: STM-200
    • Short Description: A negative allosteric modulator (NAM) of the M1 Muscarinic Receptor
    • Applications: Electrophysiology
    • CAS No.: 135541-77-4
    • MW: 7472.5 Da
  • α-Conotoxin AuIB
    Bioassay Tested
    α-Conotoxin AuIB
    An antagonist of mammalian α3/β4 neuronal nAChR that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Product Code: STC-310
    • Short Description: An antagonist of mammalian α3/β4 neuronal nAChR that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Applications: Electrophysiology
    • CAS No.: 216299-21-7
    • MW: 1572.8 Da
  • α-Conotoxin RgIA
    Bioassay Tested
    α-Conotoxin RgIA
    A potent antagonist of α9α10 nAChRs that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Product Code: STC-010
    • Short Description: A potent antagonist of α9α10 nAChRs that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Applications: Electrophysiology
    • MW: 1571 Da
  • human, rat Spexin-1
    Bioassay Tested
    human, rat Spexin-1
    A Potent Agonist of Galanin 2 and Galanin 3 Receptors
    • Product Code: SPS-100
    • Short Description: A Potent Agonist of Galanin 2 and Galanin 3 Receptors
    • Applications: Aequorin functional assay, Calcium imaging assay
    • CAS No.: 1370290-58-6
    • MW: 1620 Da
  • TAK-044
    Bioassay Tested
    TAK-044
    A Non-Selective Antagonist of Endothelin Receptors
    • Product Code: SPE-320
    • Short Description: A Non-Selective Antagonist of Endothelin Receptors
    • Applications: ETB assay, Calcium imaging assay
    • CAS No.: 157380-72-8
    • MW: 927 Da
  • [Ala1,3,11,15] Endothelin-1
    Bioassay Tested
    [Ala1,3,11,15] Endothelin-1
    A Potent Agonist of Endothelin B Receptors
    • Product Code: SPE-240
    • Short Description: A Potent Agonist of Endothelin B Receptors
    • Applications: Aequorin functional assay, Calcium imaging assay
    • CAS No.: 121204-87-3
    • MW: 2367.7 Da
  • IRL-1620
    Bioassay Tested
    IRL-1620
    A Selective and Potent Endothelin B Receptor Agonist
    • Product Code: SPE-220
    • Short Description: A Selective and Potent Endothelin B Receptor Agonist
    • Applications: Aequorin functional assay, Calcium imaging assay
    • CAS No.: 142569-99-1
    • MW: 1820 Da
  • BQ-3020
    Bioassay Tested
    BQ-3020
    A Selective and Potent Endothelin B Receptor Agonist
    • Product Code: SPE-200
    • Short Description: A Selective and Potent Endothelin B Receptor Agonist
    • Applications: Aequorin functional assay, Calcium imaging assay
    • CAS No.: 143113-45-5
    • MW: 2006 Da
  • Sarafotoxin S6b
    Bioassay Tested
    Sarafotoxin S6b
    A potent, non-selective agonist for ETA and ETB endothelin receptors
    • Product Code: SPE-160
    • Applications: Aequorin functional assay, Calcium imaging assay
    • CAS No.: 116303-65-2
    • MW: 2564 Da
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