Genetic Cardiac Diseases

Genetic Cardiac Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

132 Results
  • Anti-Na<sub>V</sub>1.5 (SCN5A) (1978-2016) Antibody
    Anti-NaV1.5 (SCN5A) (1978-2016) Antibody
    A Rabbit Polyclonal Antibody to NaV1.5 (SCN5A) (1978-2016) Channel
    • Product Code: ASC-013
    • Short Description: A Rabbit Polyclonal Antibody to NaV1.5 (SCN5A) (1978-2016) Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Mouse
    • Applications: Indirect flow cytometry, Western blot, Immunocytochemistry, Immunohistochemistry
    • Target: Sodium channel protein type 5 subunit alpha, SKM2
  • Anti-Na<sub>V</sub>1.5 (SCN5A) (493-511) Antibody
    KO Validate'
    Anti-NaV1.5 (SCN5A) (493-511) Antibody
    A Rabbit Polyclonal Antibody to NaV1.5 (SCN5A) (493-511) Channel
    • Product Code: ASC-005
    • Short Description: A Rabbit Polyclonal Antibody to NaV1.5 (SCN5A) (493-511) Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry
    • Target: Sodium channel protein type 5 subunit alpha, SKM2
  • Anti-Na<sub>V</sub>1.5 (SCN5A) (extracellular) Antibody
    Anti-NaV1.5 (SCN5A) (extracellular) Antibody
    A Rabbit Polyclonal antibody to NaV1.5 (extracellular)
    • Product Code: ASC-045
    • Short Description: A Rabbit Polyclonal antibody to NaV1.5 (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot
    • Target: Sodium channel protein type 5 subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.5, Long QT Syndrome 3, LQT3
  • Anti-Na<sub>V</sub>1.5 (SCN5A) (extracellular) Antibody-APC
    Anti-NaV1.5 (SCN5A) (extracellular) Antibody-APC
    A Rabbit Polyclonal Antibody to NaV1.5 (SCN5A) conjugated to Allophycocyanin (APC) fluorophore
    • Product Code: ASC-045-APC
    • Short Description: A Rabbit Polyclonal Antibody to NaV1.5 (SCN5A) conjugated to Allophycocyanin (APC) fluorophore
    • Host: Rabbit
    • Label: APC
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Flow cytometry
    • Target: Sodium channel protein type 5 subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.5, Long QT Syndrome 3, LQT3
  • Anti-NHERF-1/EBP50 Antibody
    Anti-NHERF-1/EBP50 Antibody
    A Rabbit Polyclonal Antibody to NHERF-1/EBP50
    • Product Code: APZ-006
    • Short Description: A Rabbit Polyclonal Antibody to NHERF-1/EBP50
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Mouse
    • Applications: Western blot
    • Target: Na+/H+ exchange regulatory cofactor 1, Ezrin-radixin-moesin-binding phosphoprotein 50, SLC9A3R1
  • Anti-PEX5L (TRIP8b) Antibody
    KO Validate'
    Anti-PEX5L (TRIP8b) Antibody
    A Rabbit Polyclonal Antibody to PEX5L (TRIP8b)
    • Product Code: APR-070
    • Short Description: A Rabbit Polyclonal Antibody to PEX5L (TRIP8b)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: PEX5R, PEX5Rp, PEX5-related protein, PEX5-like protein, Peroxin-5-related protein, PEX2-related protein, PXR2, Peroxisome biogenesis factor 5-like, TPR-containing Rab8b-interacting protein
  • Anti-PMCA3 Antibody
    Anti-PMCA3 Antibody
    A Rabbit Polyclonal Antibody to PMCA3 ATPase
    • Product Code: ACP-003
    • Short Description: A Rabbit Polyclonal Antibody to PMCA3 ATPase
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Plasma membrane Ca2+ ATPase 3, Plasma membrane calcium pump isoform 3, ATP2B3, SCAX1
  • Anti-Prostacyclin Receptor (PTGIR) (extracellular) Antibody
    Anti-Prostacyclin Receptor (PTGIR) (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Prostacyclin Receptor (PTGIR)
    • Product Code: APR-068
    • Short Description: A Rabbit Polyclonal Antibody to Prostacyclin Receptor (PTGIR)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot
    • Target: Prostanoid IP receptor, Prostaglandin I2 receptor, PGI2 receptor
  • Anti-Prostacyclin Receptor (PTGIR) (extracellular)-FITC Antibody
    Anti-Prostacyclin Receptor (PTGIR) (extracellular)-FITC Antibody
    A Rabbit Polyclonal Antibody to PTGIR (extracellular) conjugated to the fluorescent dye FITC
    • Product Code: APR-068-F
    • Short Description: A Rabbit Polyclonal Antibody to PTGIR (extracellular) conjugated to the fluorescent dye FITC
    • Host: Rabbit
    • Label: FITC
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Flow cytometry
    • Target: Prostanoid IP receptor, Prostaglandin I2 receptor, PGI2 receptor, PRIPR
  • Anti-RXFP2 (extracellular) Antibody
    Anti-RXFP2 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Relaxin Receptor 2
    • Product Code: ARR-012
    • Short Description: A Rabbit Polyclonal Antibody to Relaxin Receptor 2
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot
    • Target: Relaxin receptor 2, G-protein coupled receptor affecting testicular descent, Leucine-rich repeat-containing G-protein coupled receptor 8, GPR106, GREAT, LGR8, INSL3R
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