Genetic Cardiac Diseases

Genetic Cardiac Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

132 Results
  • Anti-Ryanodine Receptor 2 Antibody
    Anti-Ryanodine Receptor 2 Antibody
    A Rabbit Polyclonal Antibody to Ryanodine Receptor 2
    • Product Code: ARR-002
    • Short Description: A Rabbit Polyclonal Antibody to Ryanodine Receptor 2
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: RyR2, Cardiac muscle ryanodine receptor
  • Anti-SCN2B (Na<sub>V</sub>β<sub>2</sub>) Antibody
    KO Validate'
    Anti-SCN2B (NaVβ2) Antibody
    A Rabbit Polyclonal Antibody to NaVβ2 Subunit
    • Product Code: ASC-007
    • Short Description: A Rabbit Polyclonal Antibody to NaVβ2 Subunit
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Voltage-gated sodium channel subunit beta-2
  • Anti-SERCA3 Antibody
    Anti-SERCA3 Antibody
    A Rabbit Polyclonal Antibody to SERCA3 Pump
    • Product Code: ACP-014
    • Short Description: A Rabbit Polyclonal Antibody to SERCA3 Pump
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, Calcium pump 3, ATP2A3
  • Anti-SLC17A5 (Sialin) Antibody
    Anti-SLC17A5 (Sialin) Antibody
    A Rabbit Polyclonal Antibody to SLC17A5 (Sialin) Transporter
    • Product Code: AST-015
    • Short Description: A Rabbit Polyclonal Antibody to SLC17A5 (Sialin) Transporter
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Sialic acid transporter, H+/sialic acid cotransporter, Vesicular H+/aspartate-glutamate cotransporter
  • Anti-SLC22A1 Antibody
    Anti-SLC22A1 Antibody
    A Rabbit Polyclonal Antibody to Organic Cation Transporter 1
    • Product Code: ACT-011
    • Short Description: A Rabbit Polyclonal Antibody to Organic Cation Transporter 1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot
    • Target: OCT1, Organic cation transporter 1
  • Anti-TRIC-A (TMEM38A) Antibody
    Anti-TRIC-A (TMEM38A) Antibody
    A Rabbit Polyclonal Antibody to TRIC-A Channel
    • Product Code: ATC-002
    • Short Description: A Rabbit Polyclonal Antibody to TRIC-A Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunohistochemistry
    • Target: Trimeric intracellular cation channel type A, 27 kDa sarcoplasmic reticulum protein, Transmembrane protein 38A
  • Anti-TRIC-B (TMEM38B) Antibody
    Anti-TRIC-B (TMEM38B) Antibody
    A Rabbit Polyclonal Antibody to TRIC-B Channel
    • Product Code: ATC-001
    • Short Description: A Rabbit Polyclonal Antibody to TRIC-B Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunohistochemistry
    • Target: Trimeric intracellular cation channel type B, Transmembrane protein 38B
  • Anti-α1-Syntrophin (SNTA1) Antibody
    Anti-α1-Syntrophin (SNTA1) Antibody
    A Rabbit Polyclonal Antibody to α1-Syntrophin (SNTA1)
    • Product Code: APZ-021
    • Short Description: A Rabbit Polyclonal Antibody to α1-Syntrophin (SNTA1)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Syntrophin alpha 1, Syntrophin-1, 59 kDa dystrophin-associated protein A1 acidic component 1
  • Anti-β1-Syntrophin (SNTB1) Antibody
    Anti-β1-Syntrophin (SNTB1) Antibody
    A Rabbit Polyclonal Antibody to β1-Syntrophin (SNTB1)
    • Product Code: APZ-022
    • Short Description: A Rabbit Polyclonal Antibody to β1-Syntrophin (SNTB1)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot
    • Target: Syntrophin-2, SNT2B1, BSYN2, 59 kDa dystrophin-associated protein A1 basic component 1, DAPA1B, Tax interaction protein 43, TIP-43
  • Benidipine hydrochloride
    Bioassay Tested
    Benidipine hydrochloride
    A Dihydropyridine Blocker of Voltage-Gated Ca2+ Channels
    • Product Code: B-120
    • Short Description: A Dihydropyridine Blocker of Voltage-Gated Ca2+ Channels
    • CAS No.: 91599-74-5
    • MW: 542
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