Hypertension

Hypertension

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

561 Results
  • Ceratotoxin-2
    Bioassay Tested
    Ceratotoxin-2
    A potent blocker of central nervous system voltage-gated Na+ channels
    • Product Code: STC-100
    • Short Description: A potent blocker of central nervous system voltage-gated Na+ channels
    • Applications: Electrophysiology
    • MW: 4092.7 Da
  • CFTR Blocking Peptide
    CFTR Blocking Peptide
    A Blocking Peptide for Anti-CFTR Antibody
    • Product Code: BLP-CL006
    • Short Description: A Blocking Peptide for Anti-CFTR Antibody
    • Applications: Western blot, Immunohistochemistry
    • Target: CFTR
  • Charybdotoxin
    Bioassay Tested
    Charybdotoxin
    A potent broad-spectrum blocker of K+ channels, including KV1.2, KV1.3, KV1.6, KCa1.1 and KCa3.1 channels
    • Product Code: STC-325
    • Short Description: A potent broad-spectrum blocker of K+ channels, including KV1.2, KV1.3, KV1.6, KCa1.1 and KCa3.1 channels
    • Applications: Electrophysiology
    • CAS No.: 95751-30-7
    • MW: 4296 Da
  • Chlorotoxin
    Chlorotoxin
    A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Product Code: STC-460
    • Short Description: A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Applications: Cell-Based Assays, Electrophysiology, Calcium imaging assay
    • CAS No.: 163515-35-3
    • MW: 3995.8 Da
  • Chlorotoxin
    Bioassay Tested
    Chlorotoxin
    A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Product Code: RTC-450
    • Short Description: A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Applications: Cell-Based Assays, Electrophysiology, Calcium imaging assay
    • CAS No.: 163515-35-3
    • MW: 3996.7 Da
  • Cilnidipine
    Bioassay Tested
    Cilnidipine
    A Blocker of L- and N-Type CaV Channels
    • Product Code: C-135
    • Short Description: A Blocker of L- and N-Type CaV Channels
    • CAS No.: 132203-70-4
    • MW: 492.5
  • CLIC4 Blocking Peptide
    CLIC4 Blocking Peptide
    A Blocking Peptide for Anti-CLIC4 Antibody
    • Product Code: BLP-CL024
    • Short Description: A Blocking Peptide for Anti-CLIC4 Antibody
    • Applications: Western blot, Immunohistochemistry
    • Target: CLIC4
  • Co 102862
    Bioassay Tested
    Co 102862
    A Potent, State-Dependent Blocker of Neuronal NaV Channels
    • Product Code: C-160
    • Short Description: A Potent, State-Dependent Blocker of Neuronal NaV Channels
    • CAS No.: 181144-66-1
    • MW: 273.3
  • Connexin-40/GJA5 Blocking Peptide
    Connexin-40/GJA5 Blocking Peptide
    A Blocking Peptide for Anti-Connexin-40/GJA5 Antibody
    • Product Code: BLP-CC205
    • Short Description: A Blocking Peptide for Anti-Connexin-40/GJA5 Antibody
    • Applications: Western blot, Immunohistochemistry
    • Target: GJA5
  • CRLR/CALCRL (extracellular) Blocking Peptide
    CRLR/CALCRL (extracellular) Blocking Peptide
    A Blocking Peptide for Anti-CRLR/CALCRL (extracellular) Antibody
    • Product Code: BLP-CR060
    • Short Description: A Blocking Peptide for Anti-CRLR/CALCRL (extracellular) Antibody
    • Applications: Western blot, Immunohistochemistry
    • Target: CALCRL
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