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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

2041 Results
  • α-Conotoxin SI
    Bioassay Tested
    α-Conotoxin SI
    A potent and selective antagonist of the muscle-type nicotinic acetylcholine receptors (nAChRs)
    • Product Code: STC-825
    • Short Description: A potent and selective antagonist of the muscle-type nicotinic acetylcholine receptors (nAChRs)
    • Applications: Electrophysiology
    • CAS No.: 115797-06-3
    • MW: 1353.6 Da
  • ω-Conotoxin CnVIIA
    Bioassay Tested
    ω-Conotoxin CnVIIA
    A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Product Code: STC-800
    • Short Description: A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Applications: Electrophysiology
    • CAS No.: 760212-36-0
    • MW: 2848.3 Da
  • ω-Conotoxin FVIA
    Bioassay Tested
    ω-Conotoxin FVIA
    A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Product Code: STC-780
    • Short Description: A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Applications: Electrophysiology
    • MW: 2567 Da
  • ω-Conotoxin CVIF
    Bioassay Tested
    ω-Conotoxin CVIF
    A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Product Code: STC-770
    • Short Description: A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Applications: Electrophysiology
    • MW: 2665 Da
  • ω-Conotoxin CVIE
    Bioassay Tested
    ω-Conotoxin CVIE
    A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Product Code: STC-760
    • Short Description: A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Applications: Electrophysiology
    • MW: 2639 Da
  • ω-Conotoxin MVIID
    Bioassay Tested
    ω-Conotoxin MVIID
    A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Product Code: STC-751
    • Short Description: A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Applications: Electrophysiology
    • CAS No.: 153887-08-2
    • MW: 2695 Da
  • ω-Conotoxin CVIA
    Bioassay Tested
    ω-Conotoxin CVIA
    A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Product Code: STC-750
    • Short Description: A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Applications: Electrophysiology
    • MW: 2642 Da
  • µ-Conotoxin BuIIIC
    Bioassay Tested
    µ-Conotoxin BuIIIC
    A potent and selective blocker of skeletal muscle NaV1.4 voltage-gated sodium channels
    • Product Code: STC-690
    • Short Description: A potent and selective blocker of skeletal muscle NaV1.4 voltage-gated sodium channels
    • Applications: Electrophysiology
    • MW: 3006 Da
  • Ceratotoxin-1
    Bioassay Tested
    Ceratotoxin-1
    A potent blocker of neuronal NaV1.2 voltage-gated sodium channels that also inhibits NaV1.1, NaV1.4, NaV1.5 and NaV1.7 channels
    • Product Code: STC-680
    • Short Description: A potent blocker of neuronal NaV1.2 voltage-gated sodium channels that also inhibits NaV1.1, NaV1.4, NaV1.5 and NaV1.7 channels
    • Applications: Electrophysiology
    • MW: 4044.6 Da
  • µ-Conotoxin BuIIIB
    Bioassay Tested
    µ-Conotoxin BuIIIB
    A potent blocker of NaV1.3 and NaV1.4 sodium channels that also inhibits NaV1.1 and NaV1.2 subtypes
    • Product Code: STC-661
    • Short Description: A potent blocker of NaV1.3 and NaV1.4 sodium channels that also inhibits NaV1.1 and NaV1.2 subtypes
    • Applications: Electrophysiology
    • MW: 2763 Da
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