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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

2045 Results
  • µ-Conotoxin BuIIIA
    Bioassay Tested
    µ-Conotoxin BuIIIA
    A potent blocker of neuronal NaV1.2 and skeletal muscle NaV1.4 voltage-gated sodium channels
    • Product Code: STC-540
    • Short Description: A potent blocker of neuronal NaV1.2 and skeletal muscle NaV1.4 voltage-gated sodium channels
    • Applications: Electrophysiology
    • MW: 2751 Da
  • αA-Conotoxin OIVA
    Bioassay Tested
    αA-Conotoxin OIVA
    A potent antagonist of muscle α1/β1/γ/δ nicotinic acetylcholine receptors (nAChRs)
    • Product Code: STC-520
    • Short Description: A potent antagonist of muscle α1/β1/γ/δ nicotinic acetylcholine receptors (nAChRs)
    • Applications: Electrophysiology
    • CAS No.: 123456
    • MW: 1848 Da
  • α-Conotoxin GI
    Bioassay Tested
    α-Conotoxin GI
    A potent and selective antagonist of the muscle-type nicotinic acetylcholine receptor (nAChR)
    • Product Code: STC-500
    • Short Description: A potent and selective antagonist of the muscle-type nicotinic acetylcholine receptor (nAChR)
    • Applications: Electrophysiology
    • CAS No.: 76862-65-2
    • MW: 1437.6 Da
  • ω-Conotoxin SO3
    Bioassay Tested
    ω-Conotoxin SO3
    A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Product Code: STC-470
    • Short Description: A potent and selective blocker of neuronal N-type (CaV2.2) calcium channels
    • Applications: Electrophysiology
    • CAS No.: 441284-32-8
    • MW: 2561 Da
  • Chlorotoxin
    Chlorotoxin
    A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Product Code: STC-460
    • Short Description: A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Applications: Cell-Based Assays, Electrophysiology, Calcium imaging assay
    • CAS No.: 163515-35-3
    • MW: 3995.8 Da
  • µ-Conotoxin SIIIA
    Bioassay Tested
    µ-Conotoxin SIIIA
    A potent blocker of neuronal NaV1.2 channels that also inhibits NaV1.4 and NaV1.6 channels
    • Product Code: STC-450
    • Short Description: A potent blocker of neuronal NaV1.2 channels that also inhibits NaV1.4 and NaV1.6 channels
    • Applications: Electrophysiology
    • MW: 2207.5 Da
  • ω-Conotoxin CVIC
    Bioassay Tested
    ω-Conotoxin CVIC
    A potent blocker of N-type (CaV2.2) and P/Q-type (CaV2.1) voltage-gated calcium channels
    • Product Code: STC-420
    • Short Description: A potent blocker of N-type (CaV2.2) and P/Q-type (CaV2.1) voltage-gated calcium channels
    • Applications: Electrophysiology
    • MW: 2783 Da
  • ω-Conotoxin CVIB
    Bioassay Tested
    ω-Conotoxin CVIB
    A potent blocker of N-type (CaV2.2) and P/Q-type (CaV2.1) voltage-gated calcium channels
    • Product Code: STC-410
    • Short Description: A potent blocker of N-type (CaV2.2) and P/Q-type (CaV2.1) voltage-gated calcium channels
    • Applications: Electrophysiology
    • MW: 2710 Da
  • µ-Conotoxin PIIIA
    Bioassay Tested
    µ-Conotoxin PIIIA
    A potent blocker of the skeletal muscle voltage-gated sodium NaV1.4 channel that also inhibits other TTX-sensitive neuronal NaV channels
    • Product Code: STC-400
    • Short Description: A potent blocker of the skeletal muscle voltage-gated sodium NaV1.4 channel that also inhibits other TTX-sensitive neuronal NaV channels
    • Applications: Electrophysiology
    • MW: 2604 Da
  • α-Conotoxin MI
    Bioassay Tested
    α-Conotoxin MI
    A potent antagonist of muscle α1/β1/γ/δ nicotinic acetylcholine receptors (nAChRs)
    • Product Code: STC-370
    • Short Description: A potent antagonist of muscle α1/β1/γ/δ nicotinic acetylcholine receptors (nAChRs)
    • Applications: Electrophysiology
    • CAS No.: 83481-45-2
    • MW: 1493.7 Da
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