Neurodegenerative Diseases

Neurodegenerative Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.
  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

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941 Results
  • Anti-CHRM5 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Muscarinic Acetylcholine Receptor M5
    • Product Code: AMR-005
    • Short Description: A Rabbit Polyclonal Antibody to Muscarinic Acetylcholine Receptor M5
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot
    • Target: Muscarinic acetylcholine receptor M5, Cholinergic receptor muscarinic 5, mAChR M5, HM5
  • Anti-CLEC7A/Dectin-1 (extracellular) Antibody
    A Rabbit Polyclonal antibody to CLEC7A/Dectin-1 (extracellular)
    • Product Code: ALR-062
    • Short Description: A Rabbit Polyclonal antibody to CLEC7A/Dectin-1 (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunohistochemistry
    • Target: C-Type Lectin Domain Family 7 Member A, Dendritic Cell-Associated C-Type Lectin 1, DC-Associated C-Type Lectin 1, Beta-Glucan Receptor, C-Type Lectin Superfamily Member 12, CLECSF12, CD369
  • Anti-CLEC7A/Dectin-1 (extracellular)-FITC Antibody
    A Rabbit Polyclonal Antibody to CLEC7A (extracellular) conjugated to the fluorescent dye FITC
    • Product Code: ALR-062-F
    • Short Description: A Rabbit Polyclonal Antibody to CLEC7A (extracellular) conjugated to the fluorescent dye FITC
    • Host: Rabbit
    • Label: FITC
    • Reactivity: Rat, Mouse
    • Applications: Live cell imaging, Flow cytometry
    • Target: C-Type Lectin Domain Family 7 Member A, Dendritic Cell-Associated C-Type Lectin 1, DC-Associated C-Type Lectin 1, Beta-Glucan Receptor, C-Type Lectin Superfamily Member 12, CLECSF12, CD369, SCARE2
  • Anti-CLIC1 Antibody
    A Rabbit Polyclonal Antibody to CLIC1 Channel
    • Product Code: ACL-021
    • Short Description: A Rabbit Polyclonal Antibody to CLIC1 Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunofluorescence
    • Target: Cl- intracellular channel 1, Nuclear chloride ion channel 27, NCC27, Chloride channel ABP
  • Anti-CLIC5 Antibody
    A Rabbit Polyclonal Antibody to CLIC5 Channel
    • Product Code: ACL-025
    • Short Description: A Rabbit Polyclonal Antibody to CLIC5 Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: Cl- intracellular channel 5
  • Anti-CNTF Antibody
    A Rabbit Polyclonal Antibody to CNTF
    • Product Code: ANT-031
    • Short Description: A Rabbit Polyclonal Antibody to CNTF
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: Ciliary neurotrophic factor
  • Anti-Contactin-1/CNTN1 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Contactin-1 (extracellular)
    • Product Code: ANR-171
    • Short Description: A Rabbit Polyclonal Antibody to Contactin-1 (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Neural cell surface protein F3, Glycoprotein GP135, CNTN1
  • Anti-Contactin-2/CNTN2 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Contactin-2 (extracellular)
    • Product Code: ANR-172
    • Short Description: A Rabbit Polyclonal Antibody to Contactin-2 (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Axonal glycoprotein TAG-1, Axonin-1, Transient axonal glycoprotein 1, TAX-1
  • Anti-CPLX1/2 Antibody
    A Rabbit Polyclonal Antibody to Complexin-1 and Complexin-2
    • Product Code: ANR-011
    • Short Description: A Rabbit Polyclonal Antibody to Complexin-1 and Complexin-2
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot
    • Target: Complexin 1, Complexin I, Synaphin-2, Complexin 2, Complexin II, Synaphin-1
  • Anti-CRF1/CRHR1 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Corticotropin-Releasing Factor Receptor 1
    • Product Code: ACR-050
    • Short Description: A Rabbit Polyclonal Antibody to Corticotropin-Releasing Factor Receptor 1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Corticotropin-releasing factor receptor 1, CRFR1, Corticotropin-releasing hormone receptor 1, CRH-R1, CRH1
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