Neurodegenerative Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

941 Results
  • Anti-mGluR7 (extracellular) Antibody
    Anti-mGluR7 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Metabotropic Glutamate Receptor 7
    • Product Code: AGC-017
    • Short Description: A Rabbit Polyclonal Antibody to Metabotropic Glutamate Receptor 7
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: Metabotropic glutamate receptor 7, GRM7, mGlu7, Gprc1g
  • Anti-mGluR8 (extracellular) Antibody
    Anti-mGluR8 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Metabotropic Glutamate Receptor 8
    • Product Code: AGC-028
    • Short Description: A Rabbit Polyclonal Antibody to Metabotropic Glutamate Receptor 8
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Metabotropic glutamate receptor 8, GRM8, mGlu8, GPRC1H
  • Anti-NCS1 Antibody
    Anti-NCS1 Antibody
    A Rabbit Polyclonal Antibody to Neuronal Calcium Sensor 1
    • Product Code: ACS-001
    • Short Description: A Rabbit Polyclonal Antibody to Neuronal Calcium Sensor 1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Neuronal calcium sensor 1, Frequenin homolog, Frequenin-like protein, FREQ, FLUP
  • Anti-NCS1-ATTO Fluor-594 Antibody
    Anti-NCS1-ATTO Fluor-594 Antibody
    A Rabbit Polyclonal Antibody to Neuronal Calcium Sensor 1 Conjugated to the Fluorescent Dye ATTO-594
    • Product Code: ACS-001-AR
    • Short Description: A Rabbit Polyclonal Antibody to Neuronal Calcium Sensor 1 Conjugated to the Fluorescent Dye ATTO-594
    • Host: Rabbit
    • Label: ATTO 594
    • Reactivity: Human, Rat, Mouse
    • Applications: Immunofluorescence, Immunohistochemistry
    • Target: Neuronal calcium sensor 1, Frequenin homolog, Frequenin-like protein, FREQ, FLUP
  • Anti-Nectin-1/PVRL1 (extracellular) Antibody
    Anti-Nectin-1/PVRL1 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Nectin-1/PVRL1
    • Product Code: ANR-051
    • Short Description: A Rabbit Polyclonal Antibody to Nectin-1/PVRL1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: Poliovirus receptor-related protein 1, Herpes virus entry mediator C, PRR1, CD111
  • Anti-Nectin-1/PVRL1 (extracellular)-FITC Antibody
    Anti-Nectin-1/PVRL1 (extracellular)-FITC Antibody
    A Rabbit Polyclonal Antibody to TRPM2 (extracellular) conjugated to the fluorescent dye FITC
    • Product Code: ANR-051-F
    • Short Description: A Rabbit Polyclonal Antibody to TRPM2 (extracellular) conjugated to the fluorescent dye FITC
    • Host: Rabbit
    • Label: FITC
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Flow cytometry
    • Target: Poliovirus receptor-related protein 1, Herpes virus entry mediator C, PRR1, CD111
  • Anti-Nectin-2/PVRL2 (extracellular) Antibody
    Anti-Nectin-2/PVRL2 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to Nectin-2/PVRL2
    • Product Code: ANR-052
    • Short Description: A Rabbit Polyclonal Antibody to Nectin-2/PVRL2
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Poliovirus receptor-related protein 2, Herpes virus entry mediator B, PRR2, PVRR2, CD112
  • Anti-Neogenin (extracellular) Antibody
    Anti-Neogenin (extracellular) Antibody
    A Rabbit Polyclonal antibody to Neogenin (extracellular)
    • Product Code: ANR-195
    • Short Description: A Rabbit Polyclonal antibody to Neogenin (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunohistochemistry
    • Target: Neogenin 1, NEO1, NGN
  • Anti-Neogenin (extracellular)-FITC Antibody
    Anti-Neogenin (extracellular)-FITC Antibody
    A Rabbit Polyclonal Antibody to Neogenin (extracellular) conjugated to the fluorescent dye FITC
    • Product Code: ANR-195-F
    • Short Description: A Rabbit Polyclonal Antibody to Neogenin (extracellular) conjugated to the fluorescent dye FITC
    • Host: Rabbit
    • Label: FITC
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Flow cytometry
    • Target: Neogenin 1, NEO1, NGN, NTN1R2
  • Anti-Netrin-1 Antibody
    Anti-Netrin-1 Antibody
    A Rabbit Polyclonal Antibody to Netrin-1
    • Product Code: ANR-121
    • Short Description: A Rabbit Polyclonal Antibody to Netrin-1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: NTN1, MRMV4
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