Neurodegenerative Diseases

Neurodegenerative Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

941 Results
  • Anti-p75 NGF Receptor (extracellular)-ATTO Fluor-550 Antibody
    Anti-p75 NGF Receptor (extracellular)-ATTO Fluor-550 Antibody
    A Rabbit Polyclonal Antibody to Human Neurotrophin Receptor p75NTR Conjugated to the Fluorescent Dye ATTO-550
    • Product Code: ANT-007-AO
    • Short Description: A Rabbit Polyclonal Antibody to Human Neurotrophin Receptor p75NTR Conjugated to the Fluorescent Dye ATTO-550
    • Host: Rabbit
    • Label: ATTO 550
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: p75NTR, p75 Neurotrophin receptor, Low affinity NGF receptor, TNFR superfamily member 16, TNFRSF16, CD271
  • Anti-p75 NGF Receptor (extracellular)-FITC Antibody
    Anti-p75 NGF Receptor (extracellular)-FITC Antibody
    A Rabbit Polyclonal Antibody to Human Neurotrophin Receptor p75NTR Conjugated to the Fluorescent Dye FITC
    • Product Code: ANT-007-F
    • Short Description: A Rabbit Polyclonal Antibody to Human Neurotrophin Receptor p75NTR Conjugated to the Fluorescent Dye FITC
    • Host: Rabbit
    • Label: FITC
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Flow cytometry
    • Target: p75NTR, p75 Neurotrophin receptor, Low affinity NGF receptor, TNFR superfamily member 16, TNFRSF16, CD271
  • Anti-p75 NGF Receptor (intracellular) Antibody
    Anti-p75 NGF Receptor (intracellular) Antibody
    A Rabbit Polyclonal Antibody to Human Neurotrophin Receptor p75NTR
    • Product Code: ANT-011
    • Short Description: A Rabbit Polyclonal Antibody to Human Neurotrophin Receptor p75NTR
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: p75NTR, p75 Neurotrophin receptor, Low affinity NGF receptor, TNFR superfamily member 16, TNFRSF16, CD271
  • Anti-pan ASIC (extracellular) Antibody
    Anti-pan ASIC (extracellular) Antibody
    A Rabbit Polyclonal Antibody to ASIC Channels (ASIC1, ASIC2, ASIC3, ASIC4)
    • Product Code: ASC-031
    • Short Description: A Rabbit Polyclonal Antibody to ASIC Channels (ASIC1, ASIC2, ASIC3, ASIC4)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: Acid-sensing ion channel, Acid-sensing (proton-gated) ion channel, ACCN, ACCN2, ACCN3, ACCN4
  • Anti-Pannexin 1 Antibody
    KO Validate'
    Anti-Pannexin 1 Antibody
    A Rabbit Polyclonal Antibody to Pannexin 1
    • Product Code: ACC-234
    • Short Description: A Rabbit Polyclonal Antibody to Pannexin 1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: PANX1, PX1, MRS1, UNQ2529
  • Anti-Parkin Antibody
    Anti-Parkin Antibody
    A Rabbit Polyclonal antibody to Parkin
    • Product Code: ANR-103
    • Short Description: A Rabbit Polyclonal antibody to Parkin
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: E3 Ubiquitin-Protein Ligase Parkin, Parkin RBR E3 ubiquitin-protein ligase, Parkinson Juvenile Disease Protein 2, PARK2, PRKN
  • Anti-Periaxin Antibody
    Anti-Periaxin Antibody
    A Rabbit Polyclonal Antibody to Periaxin
    • Product Code: ANR-091
    • Short Description: A Rabbit Polyclonal Antibody to Periaxin
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: PRX, CMT4F
  • Anti-PICK1 Antibody
    Anti-PICK1 Antibody
    A Rabbit Polyclonal Antibody to PICK1
    • Product Code: APZ-014
    • Short Description: A Rabbit Polyclonal Antibody to PICK1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: PRKCA-binding protein, PRKCABP, Protein interacting with C kinase 1, Protein interacting with PRKCA1, Protein kinase C-alpha-binding protein
  • Anti-Presenilin-1 Antibody
    Anti-Presenilin-1 Antibody
    A Rabbit Polyclonal Antibody to Presenilin-1
    • Product Code: AIP-011
    • Short Description: A Rabbit Polyclonal Antibody to Presenilin-1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: PSEN1, PS-1, Psnl1
  • Anti-Presenilin-1-ATTO Fluor-488 Antibody
    Anti-Presenilin-1-ATTO Fluor-488 Antibody
    A Rabbit Polyclonal Antibody to Presenilin-1 Conjugated to the Fluorescent Dye ATTO-488
    • Product Code: AIP-011-AG
    • Short Description: A Rabbit Polyclonal Antibody to Presenilin-1 Conjugated to the Fluorescent Dye ATTO-488
    • Host: Rabbit
    • Label: ATTO 488
    • Reactivity: Human, Rat, Mouse
    • Applications: Immunofluorescence, Immunohistochemistry
    • Target: PSEN1, PS-1, Psnl1
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