Neurodegenerative Diseases

Neurodegenerative Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

941 Results
  • Anti-Presenilin-2 Antibody
    Anti-Presenilin-2 Antibody
    A Rabbit Polyclonal Antibody to Presenilin-2
    • Product Code: AIP-012
    • Short Description: A Rabbit Polyclonal Antibody to Presenilin-2
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Psen2, Ps2, Psnl2, AD3LP, AD5, E5-1 STM-2
  • Anti-proGDNF Antibody
    Anti-proGDNF Antibody
    A Rabbit Polyclonal Antibody to proGDNF
    • Product Code: ANT-026
    • Short Description: A Rabbit Polyclonal Antibody to proGDNF
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot
    • Target: Glial cell line-derived neurotrophic factor precursor
  • Anti-Progranulin Antibody
    Anti-Progranulin Antibody
    A Rabbit Polyclonal antibody to Progranulin
    • Product Code: ANR-178
    • Short Description: A Rabbit Polyclonal antibody to Progranulin
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Granulin Precursor, PGRN, Epithelin Precursor, Glycoprotein 88, GP88, PC Cell-Derived Growth Factor, PCDGF, GRN
  • Anti-proNGF Antibody
    Anti-proNGF Antibody
    A Rabbit Polyclonal Antibody to proNGF
    • Product Code: ANT-005
    • Short Description: A Rabbit Polyclonal Antibody to proNGF
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Nerve growth factor precursor
  • Anti-proNT-3 Antibody
    Anti-proNT-3 Antibody
    A Rabbit Polyclonal Antibody to proNT-3
    • Product Code: ANT-012
    • Short Description: A Rabbit Polyclonal Antibody to proNT-3
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: pro-Neurotrophin 3, proNTF3
  • Anti-PSD-93 Antibody
    KO Validate'
    Anti-PSD-93 Antibody
    A Rabbit Polyclonal Antibody to PSD-93
    • Product Code: APZ-002
    • Short Description: A Rabbit Polyclonal Antibody to PSD-93
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry
    • Target: Discs large homolog 2, Dlg2, Chapsyn-110
  • Anti-PSD-95 Antibody
    Anti-PSD-95 Antibody
    A Rabbit Polyclonal Antibody to PSD-95
    • Product Code: APZ-009
    • Short Description: A Rabbit Polyclonal Antibody to PSD-95
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Postsynaptic density protein 95, Discs large homolog 4, DLG4, Synapse-associated protein 90, SAP-90, Tax interaction protein 15
  • Anti-PTGFRN (extracellular) Antibody
    Anti-PTGFRN (extracellular) Antibody
    A Rabbit polyclonal antibody to PTGFRN (extracellular)
    • Product Code: ANR-212
    • Short Description: A Rabbit polyclonal antibody to PTGFRN (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunohistochemistry
    • Target: Prostaglandin F2 Receptor Inhibitor, CD9 Partner 1, CD9P-1, FPRP, Glu-Trp-Ile EWI motif-containing protein F, EWI-F, CD315
  • Anti-RGMA (extracellular) Antibody
    Anti-RGMA (extracellular) Antibody
    A Rabbit polyclonal antibody to RGMA (extracellular).
    • Product Code: ANR-126
    • Short Description: A Rabbit polyclonal antibody to RGMA (extracellular).
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunohistochemistry
    • Target: Repulsive Guidance Molecule A, RGM Domain Family Member A, Repulsive Guidance Molecule BMP Co-Receptor A, RGMa
  • Anti-RIM1 Antibody
    Anti-RIM1 Antibody
    A Rabbit Polyclonal Antibody to RIM1
    • Product Code: AIP-014
    • Short Description: A Rabbit Polyclonal Antibody to RIM1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot
    • Target: Regulating synaptic membrane exocytosis 1, Rab-3-interacting molecule 1, RIMS1
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