Neurodegenerative Diseases

Neurodegenerative Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

941 Results
  • Anti-GFAP-ATTO Fluor-647N Antibody
    Anti-GFAP-ATTO Fluor-647N Antibody
    A Rabbit Polyclonal Antibody to GFAP conjugated to the fluorescent dye ATTO Fluor-647N
    • Product Code: AFP-001-FRN
    • Short Description: A Rabbit Polyclonal Antibody to GFAP conjugated to the fluorescent dye ATTO Fluor-647N
    • Host: Rabbit
    • Label: ATTO 647N
    • Reactivity: Rat, Mouse
    • Applications: Immunocytochemistry, Immunohistochemistry
    • Target: Glial fibrillary acidic protein
  • Anti-GFR alpha 1 (extracellular) Antibody
    Anti-GFR alpha 1 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to GDNF Family Receptor α1
    • Product Code: ANT-021
    • Short Description: A Rabbit Polyclonal Antibody to GDNF Family Receptor α1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: GFRA1, GFRα1, GDNF family receptor α1, GDNF receptor alpha 1, Ret ligand 1, RETL1, TRNR1
  • Anti-GFR alpha 3 (extracellular) Antibody
    Anti-GFR alpha 3 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to GDNF Family Receptor α3
    • Product Code: ANT-023
    • Short Description: A Rabbit Polyclonal Antibody to GDNF Family Receptor α3
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot
    • Target: GFRA3, GFRα3, GDNF family receptor α3, GDNF receptor alpha 3
  • Anti-GFR alpha 4 (extracellular) Antibody
    Anti-GFR alpha 4 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to GDNF Family Receptor α4
    • Product Code: ANT-024
    • Short Description: A Rabbit Polyclonal Antibody to GDNF Family Receptor α4
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: GFRA4, GFRα4, GDNF family receptor α4, GDNF receptor alpha 4, Persephin receptor
  • Anti-GIRK2 (K<sub>ir</sub>3.2) Antibody
    KO Validate'
    Anti-GIRK2 (Kir3.2) Antibody
    A Rabbit Polyclonal Antibody to GIRK2 (Kir3.2) Channel
    • Product Code: APC-006
    • Short Description: A Rabbit Polyclonal Antibody to GIRK2 (Kir3.2) Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry
    • Target: G protein-activated inward rectifier potassium channel 2, Kcnj6
  • Anti-GluR1 (GluA1) (extracellular) Antibody
    KO Validate'
    Anti-GluR1 (GluA1) (extracellular) Antibody
    A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 1 (GluR1)
    • Product Code: AGC-004
    • Short Description: A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 1 (GluR1)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
    • Target: AMPA Receptor 1, Glutamate receptor 1, Ionotropic glutamate receptor 1, AMPA-selective glutamate receptor 1, GRIA1, GluR-A, GluR-K1
  • Anti-GluR1 (GluA1) (extracellular)-ATTO Fluor-594 Antibody
    KO Validate'
    Anti-GluR1 (GluA1) (extracellular)-ATTO Fluor-594 Antibody
    A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 1 (GluR1) Conjugated to the Fluorescent Dye ATTO-594
    • Product Code: AGC-004-AR
    • Short Description: A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 1 (GluR1) Conjugated to the Fluorescent Dye ATTO-594
    • Host: Rabbit
    • Label: ATTO 594
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Immunocytochemistry, Immunofluorescence
    • Target: AMPA Receptor 1, Glutamate receptor 1, Ionotropic glutamate receptor 1, AMPA-selective glutamate receptor 1, GRIA1, GluR-A, GluR-K1
  • Anti-GluR2 (GluA2) (extracellular) Antibody
    KO Validate'
    Anti-GluR2 (GluA2) (extracellular) Antibody
    A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 2 (GluR2)
    • Product Code: AGC-005
    • Short Description: A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 2 (GluR2)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry
    • Target: AMPA receptor 2, Glutamate receptor 2, Ionotropic glutamate receptor 2, AMPA-selective glutamate receptor 2, GRIA2, GluR-B, GluR-K2
  • Anti-GluR2 (GluA2) (extracellular)-ATTO Fluor-488 Antibody
    KO Validate'
    Anti-GluR2 (GluA2) (extracellular)-ATTO Fluor-488 Antibody
    A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 2 (GluR2) Conjugated to the Fluorescent Dye ATTO-488
    • Product Code: AGC-005-AG
    • Short Description: A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 2 (GluR2) Conjugated to the Fluorescent Dye ATTO-488
    • Host: Rabbit
    • Label: ATTO 488
    • Reactivity: Rat, Mouse
    • Applications: Immunofluorescence, Immunohistochemistry
    • Target: AMPA receptor 2, Glutamate receptor 2, Ionotropic glutamate receptor 2, AMPA-selective glutamate receptor 2, GRIA2, GluR-B, GluR-K2
  • Anti-GluR3 (GluA3) (extracellular) Antibody
    Anti-GluR3 (GluA3) (extracellular) Antibody
    A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 3 (GluR3)
    • Product Code: AGC-010
    • Short Description: A Rabbit Polyclonal Antibody to AMPA-Selective Glutamate Receptor 3 (GluR3)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Live cell imaging, Western blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry
    • Target: AMPA receptor 3, Glutamate receptor 3, Ionotropic glutamate receptor 3, AMPA-selective glutamate receptor 3, GRIA3, GluR-C, GluR-K3
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