Neurodegenerative Diseases

Neurodegenerative Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

941 Results
  • Anti-K<sub>V</sub>1.1 (KCNA1) Antibody
    Anti-KV1.1 (KCNA1) Antibody
    A Rabbit Polyclonal Antibody to KV1.1 (KCNA1) Channel
    • Product Code: APC-009
    • Short Description: A Rabbit Polyclonal Antibody to KV1.1 (KCNA1) Channel
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry
    • Target: Potassium voltage-gated channel subfamily A member 1
  • Anti-L1CAM (extracellular) Antibody
    Anti-L1CAM (extracellular) Antibody
    A Rabbit Polyclonal antibody to L1CAM (extracellular)
    • Product Code: ANR-047
    • Short Description: A Rabbit Polyclonal antibody to L1CAM (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunohistochemistry
    • Target: L1 Cell Adhesion Molecule, Neural Cell Adhesion Molecule L1, NCAM-L1, CAML1, CD171
  • Anti-LETM1 Antibody
    Anti-LETM1 Antibody
    A Rabbit Polyclonal Antibody to LETM1
    • Product Code: ANT-183
    • Short Description: A Rabbit Polyclonal Antibody to LETM1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot
    • Target: Leucine zipper-EF-hand-containing transmembrane protein 1, LETM1 and EF-hand domain-containing protein 1 mitochondrial, Mitochondrial proton/calcium exchanger protein, Mdm38 homolog
  • Anti-LINGO-1 (extracellular) Antibody
    Anti-LINGO-1 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to LINGO-1
    • Product Code: ANT-032
    • Short Description: A Rabbit Polyclonal Antibody to LINGO-1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, LRRN6A, LERN1
  • Anti-LRRK2 Antibody
    Anti-LRRK2 Antibody
    A Rabbit Polyclonal Antibody to LRRK2
    • Product Code: ANR-102
    • Short Description: A Rabbit Polyclonal Antibody to LRRK2
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Leucine-rich repeat kinase 2, Parkinson disease (Autosomal dominant) 8, PARK8, Roco2, RIPK7, Dardarin
  • Anti-MAGI2/AIP1 Antibody
    Anti-MAGI2/AIP1 Antibody
    A Rabbit Polyclonal Antibody to MAGI2
    • Product Code: APZ-052
    • Short Description: A Rabbit Polyclonal Antibody to MAGI2
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot
    • Target: Membrane associated guanylate kinase, WW and PDZ domain containing 2, Activin receptor-interacting protein 1, Acvrip1, Atrophin-1-interacting protein 1
  • Anti-MANF/ARMET Antibody
    Anti-MANF/ARMET Antibody
    A Rabbit Polyclonal Antibody to MANF
    • Product Code: ANT-028
    • Short Description: A Rabbit Polyclonal Antibody to MANF
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich mutated in early stage tumors, ARP
  • Anti-MANF/ARMET-ATTO Fluor-594 Antibody
    Anti-MANF/ARMET-ATTO Fluor-594 Antibody
    A Rabbit Polyclonal Antibody to MANF Conjugated to the Fluorescent Dye ATTO-594
    • Product Code: ANT-028-AR
    • Short Description: A Rabbit Polyclonal Antibody to MANF Conjugated to the Fluorescent Dye ATTO-594
    • Host: Rabbit
    • Label: ATTO 594
    • Reactivity: Rat, Mouse
    • Applications: Immunofluorescence, Immunohistochemistry
    • Target: Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich mutated in early stage tumors, ARP
  • Anti-MCU Antibody
    Anti-MCU Antibody
    A Rabbit Polyclonal Antibody to Mitochondrial Calcium Uniporter
    • Product Code: ACC-328
    • Short Description: A Rabbit Polyclonal Antibody to Mitochondrial Calcium Uniporter
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Mitochondrial calcium uniporter, HsMCU, Coiled-coil domain-containing protein 109A, Ccdc109a, C10orf42
  • Anti-MCUR1 (CCDC90A) Antibody
    Anti-MCUR1 (CCDC90A) Antibody
    A Rabbit Polyclonal Antibody to Mitochondrial Calcium Uniporter Regulator 1
    • Product Code: ACC-321
    • Short Description: A Rabbit Polyclonal Antibody to Mitochondrial Calcium Uniporter Regulator 1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot
    • Target: Mitochondrial calcium uniporter regulator 1, MCU regulator 1, Coiled-coil domain-containing protein 90A mitochondrial
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