Neurodegenerative Diseases

Neurodegenerative Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

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941 Results
  • Anti-Syntaxin 1 Antibody
    Anti-Syntaxin 1 Antibody
    A Rabbit Polyclonal Antibody to Syntaxin 1
    • Product Code: ANR-002
    • Short Description: A Rabbit Polyclonal Antibody to Syntaxin 1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: STX1A, Synaptotagmin-associated 35 kDa protein, P35A, P35-1, Neuron-specific antigen HPC-1
  • Anti-TMEM106B (extracellular) Antibody
    Anti-TMEM106B (extracellular) Antibody
    A Rabbit Polyclonal antibody to TMEM106B (extracellular)
    • Product Code: ANR-177
    • Short Description: A Rabbit Polyclonal antibody to TMEM106B (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Indirect flow cytometry, Live cell imaging, Western blot, Immunohistochemistry
    • Target: Transmembrane Protein 106B
  • Anti-TMEM119 (extracellular) Antibody
    Anti-TMEM119 (extracellular) Antibody
    A Rabbit Polyclonal Antibody to TMEM119 (extracellular)
    • Product Code: ANR-175
    • Short Description: A Rabbit Polyclonal Antibody to TMEM119 (extracellular)
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Indirect flow cytometry, Western blot
    • Target: Transmembrane Protein 119, Osteoblast induction factor, OBIF
  • Anti-TMEM119 (extracellular)-APC Antibody
    Anti-TMEM119 (extracellular)-APC Antibody
    A Rabbit Polyclonal Antibody to TMEM119 (extracellular) conjugated to the fluorescent dye Allophycocyanin (APC)
    • Product Code: ANR-175-APC
    • Short Description: A Rabbit Polyclonal Antibody to TMEM119 (extracellular) conjugated to the fluorescent dye Allophycocyanin (APC)
    • Host: Rabbit
    • Label: APC
    • Reactivity: Rat, Mouse
    • Applications: Live cell imaging, Flow cytometry
    • Target: Transmembrane Protein 119, Osteoblast induction factor, OBIF
  • Anti-TMEM119 (extracellular)-FITC Antibody
    Anti-TMEM119 (extracellular)-FITC Antibody
    A Rabbit Polyclonal Antibody to TMEM119 (extracellular) conjugated to the fluorescent dye FITC
    • Product Code: ANR-175-F
    • Short Description: A Rabbit Polyclonal Antibody to TMEM119 (extracellular) conjugated to the fluorescent dye FITC
    • Host: Rabbit
    • Label: FITC
    • Reactivity: Rat, Mouse
    • Applications: Flow cytometry
    • Target: Transmembrane Protein 119, Osteoblast induction factor, OBIF
  • Anti-TMEM175 Antibody
    Anti-TMEM175 Antibody
    A Rabbit Polyclonal antibody to TMEM175
    • Product Code: APC-175
    • Short Description: A Rabbit Polyclonal antibody to TMEM175
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Transmembrane Protein 175, Endosomal/Lysosomal Proton Channel TMEM175
  • Anti-TMEM66 Antibody
    Anti-TMEM66 Antibody
    A Rabbit Polyclonal Antibody to TMEM66
    • Product Code: ACC-067
    • Short Description: A Rabbit Polyclonal Antibody to TMEM66
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Store-operated calcium entry-associated regulatory factor, SOCE-associated regulatory factor, SARAF, Transmembrane protein 66
  • Anti-TMEM66-ATTO Fluor-594 Antibody
    Anti-TMEM66-ATTO Fluor-594 Antibody
    A Rabbit Polyclonal Antibody to TMEM66 Conjugated to the Fluorescent Dye ATTO-594
    • Product Code: ACC-067-AR
    • Short Description: A Rabbit Polyclonal Antibody to TMEM66 Conjugated to the Fluorescent Dye ATTO-594
    • Host: Rabbit
    • Label: ATTO 594
    • Reactivity: Human, Rat, Mouse
    • Applications: Immunofluorescence, Immunohistochemistry
    • Target: Store-operated calcium entry-associated regulatory factor, SOCE-associated regulatory factor, SARAF, Transmembrane protein 66
  • Anti-TPCN1 Antibody
    Anti-TPCN1 Antibody
    A Rabbit Polyclonal Antibody to Two Pore Calcium Channel Protein 1
    • Product Code: ACC-071
    • Short Description: A Rabbit Polyclonal Antibody to Two Pore Calcium Channel Protein 1
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Two pore calcium channel protein 1, Voltage-dependent calcium channel protein TPC1, Two pore segment channel 1
  • Anti-TPCN2 Antibody
    KO Validate'
    Anti-TPCN2 Antibody
    A Rabbit Polyclonal Antibody to Two Pore Calcium Channel Protein 2
    • Product Code: ACC-072
    • Short Description: A Rabbit Polyclonal Antibody to Two Pore Calcium Channel Protein 2
    • Host: Rabbit
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: Two pore calcium channel protein 2, Voltage-dependent calcium channel protein TPC2, SHEP10
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