Neurodegenerative Diseases

Neurodegenerative Diseases

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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

944 Results
  • Guinea Pig Anti-PSD-95 Antibody
    Guinea Pig Anti-PSD-95 Antibody
    A Guinea Pig Polyclonal Antibody to PSD-95
    • Product Code: APZ-009-GP
    • Short Description: A Guinea Pig Polyclonal Antibody to PSD-95
    • Host: Guinea Pig
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot
    • Target: Postsynaptic density protein 95, Discs large homolog 4, DLG4, Synapse-associated protein 90, SAP-90, Tax interaction protein 15, MRD62
  • Guinea pig Anti-SCN2A (Na<sub>V</sub>1.2) Antibody
    Guinea pig Anti-SCN2A (NaV1.2) Antibody
    A Guinea Pig Polyclonal Antibody to SCN2A (NaV1.2) Channel
    • Product Code: ASC-002-GP
    • Short Description: A Guinea Pig Polyclonal Antibody to SCN2A (NaV1.2) Channel
    • Host: Guinea Pig
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunofluorescence, Immunohistochemistry
    • Target: BII, Brain type II Na+ channel, Sodium channel protein type 2 subunit alpha
  • Guinea Pig Anti-Synaptophysin Antibody
    Guinea Pig Anti-Synaptophysin Antibody
    A Guinea Pig Polyclonal Antibody to Synaptophysin
    • Product Code: ANR-013-GP
    • Short Description: A Guinea Pig Polyclonal Antibody to Synaptophysin
    • Host: Guinea Pig
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Major synaptic vesicle protein p38, SYP
  • Guinea Pig Anti-Synaptotagmin-1 (SYT1) Antibody
    Guinea Pig Anti-Synaptotagmin-1 (SYT1) Antibody
    A Guinea Pig Polyclonal Antibody to Anti-Synaptotagmin-1 (SYT1)
    • Product Code: ANR-003-GP
    • Short Description: A Guinea Pig Polyclonal Antibody to Anti-Synaptotagmin-1 (SYT1)
    • Host: Guinea Pig
    • Label: Unconjugated
    • Reactivity: Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Synaptotagmin I, SytI, p65, SVP65
  • Guinea Pig Anti-TrkB (extracellular) Antibody
    Guinea Pig Anti-TrkB (extracellular) Antibody
    A Guinea Pig Polyclonal Antibody to TrkB
    • Product Code: ANT-019-GP
    • Short Description: A Guinea Pig Polyclonal Antibody to TrkB
    • Host: Guinea Pig
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Neurotrophic tyrosine kinase receptor type 2, NTRK2, BDNF/NT-3 growth factors receptor, TrkB Tyrosine Kinase
  • Guinea pig Anti-Vesicular GABA Transporter (VGAT) Antibody
    Guinea pig Anti-Vesicular GABA Transporter (VGAT) Antibody
    A Guinea Pig Polyclonal Antibody to Vesicular GABA Transporter
    • Product Code: AGT-005-GP
    • Short Description: A Guinea Pig Polyclonal Antibody to Vesicular GABA Transporter
    • Host: Guinea Pig
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Vesicular inhibitory amino acid transporter, VIAAT, GABA and glycine transporter, rGVAT, SLC32A1
  • Guinea Pig Anti-VGLUT1 Antibody
    Guinea Pig Anti-VGLUT1 Antibody
    A Guinea Pig Polyclonal Antibody to VGLUT1
    • Product Code: AGC-035-GP
    • Short Description: A Guinea Pig Polyclonal Antibody to VGLUT1
    • Host: Guinea Pig
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Vesicular glutamate transporter 1, Brain-specific Na+-dependent inorganic phosphate cotransporter, BNPI, SLC17A7
  • Guinea Pig Anti-VGLUT2 Antibody
    Guinea Pig Anti-VGLUT2 Antibody
    A Guinea Pig Polyclonal Antibody to Vesicular Glutamate Transporter 2
    • Product Code: AGC-036-GP
    • Short Description: A Guinea Pig Polyclonal Antibody to Vesicular Glutamate Transporter 2
    • Host: Guinea Pig
    • Label: Unconjugated
    • Reactivity: Human, Rat, Mouse
    • Applications: Western blot, Immunohistochemistry
    • Target: Vesicular glutamate transporter 2, Differentiation-associated Na+-dependent inorganic phosphate cotransporter, DNPI, SLC17A6
  • GV-58
    Bioassay Tested
    GV-58
    An Activator of CaV2.2 and CaV2.1 Ca2+ Channels
    • Product Code: G-140
    • Short Description: An Activator of CaV2.2 and CaV2.1 Ca2+ Channels
    • CAS No.: 1402821-41-3
    • MW: 374.2
  • GW 791343 hydrochloride
    Bioassay Tested
    GW 791343 hydrochloride
    A Negative Allosteric Modulator of Human P2X7 Receptors
    • Product Code: G-115
    • Short Description: A Negative Allosteric Modulator of Human P2X7 Receptors
    • CAS No.: 309712-55-8
    • MW: 483.81
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