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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

970 Results
  • Wasabi Receptor Toxin
    Bioassay Tested
    Wasabi Receptor Toxin
    A cell-penetrating activator of TRPA1 channels
    • Product Code: STW-200
    • Short Description: A cell-penetrating activator of TRPA1 channels
    • Applications: Electrophysiology
    • CAS No.: 2569291-86-5
    • MW: 3855.3 Da
  • Zacopride (hydrochloride)
    Bioassay Tested
    Zacopride (hydrochloride)
    A Potent Antagonist of 5-HT3 Receptors and an Agonist of 5-HT4 Receptors
    • Product Code: Z-110
    • Short Description: A Potent Antagonist of 5-HT3 Receptors and an Agonist of 5-HT4 Receptors
    • CAS No.: 101303-98-4
    • MW: 346.25
  • µ-Conotoxin BuIIIA
    Bioassay Tested
    µ-Conotoxin BuIIIA
    A potent blocker of neuronal NaV1.2 and skeletal muscle NaV1.4 voltage-gated sodium channels
    • Product Code: STC-540
    • Short Description: A potent blocker of neuronal NaV1.2 and skeletal muscle NaV1.4 voltage-gated sodium channels
    • Applications: Electrophysiology
    • MW: 2751 Da
  • µ-Conotoxin BuIIIB
    Bioassay Tested
    µ-Conotoxin BuIIIB
    A potent blocker of NaV1.3 and NaV1.4 sodium channels that also inhibits NaV1.1 and NaV1.2 subtypes
    • Product Code: STC-661
    • Short Description: A potent blocker of NaV1.3 and NaV1.4 sodium channels that also inhibits NaV1.1 and NaV1.2 subtypes
    • Applications: Electrophysiology
    • MW: 2763 Da
  • µ-Conotoxin BuIIIC
    Bioassay Tested
    µ-Conotoxin BuIIIC
    A potent and selective blocker of skeletal muscle NaV1.4 voltage-gated sodium channels
    • Product Code: STC-690
    • Short Description: A potent and selective blocker of skeletal muscle NaV1.4 voltage-gated sodium channels
    • Applications: Electrophysiology
    • MW: 3006 Da
  • µ-Conotoxin CnIIIC
    Bioassay Tested
    µ-Conotoxin CnIIIC
    A potent blocker of skeletal muscle NaV1.4 and neuronal NaV1.2 sodium channels, which also inhibits the α3/β2 nAChR
    • Product Code: STC-640
    • Short Description: A potent blocker of skeletal muscle NaV1.4 and neuronal NaV1.2 sodium channels, which also inhibits the α3/β2 nAChR
    • Applications: Electrophysiology
    • MW: 2376 Da
  • µ-Conotoxin GIIIA
    Bioassay Tested
    µ-Conotoxin GIIIA
    A potent and selective blocker of skeletal muscle NaV1.4 voltage-gated sodium channels
    • Product Code: STC-280
    • Short Description: A potent and selective blocker of skeletal muscle NaV1.4 voltage-gated sodium channels
    • Applications: Electrophysiology
    • CAS No.: 129129-65-3
    • MW: 2609 Da
  • µ-Conotoxin GIIIB
    Bioassay Tested
    µ-Conotoxin GIIIB
    A selective blocker of skeletal muscle NaV1.4 channels
    • Product Code: C-270
    • Short Description: A selective blocker of skeletal muscle NaV1.4 channels
    • Applications: Electrophysiology
    • CAS No.: 140678-12-2
    • MW: 2640 Da
  • µ-Conotoxin PIIIA
    Bioassay Tested
    µ-Conotoxin PIIIA
    A potent blocker of the skeletal muscle voltage-gated sodium NaV1.4 channel that also inhibits other TTX-sensitive neuronal NaV channels
    • Product Code: STC-400
    • Short Description: A potent blocker of the skeletal muscle voltage-gated sodium NaV1.4 channel that also inhibits other TTX-sensitive neuronal NaV channels
    • Applications: Electrophysiology
    • MW: 2604 Da
  • µ-Conotoxin SIIIA
    Bioassay Tested
    µ-Conotoxin SIIIA
    A potent blocker of neuronal NaV1.2 channels that also inhibits NaV1.4 and NaV1.6 channels
    • Product Code: STC-450
    • Short Description: A potent blocker of neuronal NaV1.2 channels that also inhibits NaV1.4 and NaV1.6 channels
    • Applications: Electrophysiology
    • MW: 2207.5 Da
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