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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.
  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

  • FAQ 3FAQ 3FAQ 3FAQ 3

970 Results
  • α-Conotoxin MII
    A potent and selective antagonist of neuronal α3β2 and α6β2*-containing nicotinic acetylcholine receptors (nAChRs)
    • Product Code: STC-040
    • Short Description: A potent and selective antagonist of neuronal α3β2 and α6β2*-containing nicotinic acetylcholine receptors (nAChRs)
    • Applications: Electrophysiology
    • CAS No.: 175735-93-0
    • MW: 1711 Da
  • α-Conotoxin MrIC
    An α7 nAChR potent antagonist that functions as a PAM-dependent biased agonist
    • Product Code: STC-320
    • Short Description: An α7 nAChR potent antagonist that functions as a PAM-dependent biased agonist
    • Applications: Electrophysiology
    • MW: 1835 Da
  • α-Conotoxin PeIA
    An antagonist of neuronal nAChRs (α9α10, α6-containing, and α3/β2) that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Product Code: STC-970
    • Short Description: An antagonist of neuronal nAChRs (α9α10, α6-containing, and α3/β2) that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Applications: Electrophysiology
    • CAS No.: 866876-88-2
    • MW: 1652 Da
  • α-Conotoxin RgIA
    A potent antagonist of α9α10 nAChRs that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Product Code: STC-010
    • Short Description: A potent antagonist of α9α10 nAChRs that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Applications: Electrophysiology
    • MW: 1571 Da
  • α-Conotoxin TxID
    A potent antagonist of α3β4 nAChRs that also inhibits α6/α3β4 nicotinic acetylcholine receptors
    • Product Code: STC-110
    • Short Description: A potent antagonist of α3β4 nAChRs that also inhibits α6/α3β4 nicotinic acetylcholine receptors
    • Applications: Electrophysiology
    • CAS No.: 1496617-64-1
    • MW: 1489.8 Da
  • α-Conotoxin Vc1.1
    A potent antagonist of α9α10 nAChRs and agonist of GABA(B) receptors
    • Product Code: STV-500
    • Short Description: A potent antagonist of α9α10 nAChRs and agonist of GABA(B) receptors
    • Applications: Electrophysiology
    • CAS No.: 740980-24-9
    • MW: 1807 Da
  • α-Dendrotoxin
    A potent and selective blocker of neuronal KV1.1, KV1.2, KV1.6 potassium channels
    • Product Code: D-350
    • Short Description: A potent and selective blocker of neuronal KV1.1, KV1.2, KV1.6 potassium channels
    • Applications: Electrophysiology
    • CAS No.: 74504-53-3
    • MW: 7047 Da
  • α-Dendrotoxin-ATTO Fluor-647N
    A fluorescent probe for imaging and sensitive detection of Kv1.1, Kv1.2, and Kv1.6 channels.
    • Product Code: D-350-FRN
    • Short Description: A fluorescent probe for imaging and sensitive detection of Kv1.1, Kv1.2, and Kv1.6 channels.
    • Label: ATTO 647N
    • Applications: Electrophysiology, Direct flow cytometry, Fluorescence staining, Live cell imaging, Immunofluorescence
    • MW: ~7990 Da
  • α-MSH
    A potent agonist for melanocortin receptors, primarily involved in pigmentation, inflammation control, and appetite regulation
    • Product Code: GPM-100
    • Short Description: A potent agonist for melanocortin receptors, primarily involved in pigmentation, inflammation control, and appetite regulation
    • Applications: Melanin production assay
    • CAS No.: 581-05-5
    • MW: 1665 Da
  • α1A-Adrenergic Receptor (extracellular) Blocking Peptide
    A Blocking Peptide for Anti-alpha1A-Adrenergic Receptor (extracellular) Antibody
    • Product Code: BLP-AR015
    • Short Description: A Blocking Peptide for Anti-alpha1A-Adrenergic Receptor (extracellular) Antibody
    • Applications: Western blot, Immunohistochemistry
    • Target: ADRA1A
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