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  • The expected molecular weight (MW) listed in the product datasheet is based solely on the size of the target protein’s amino acid sequence. It’s important to remember that many factors can affect the banding pattern of your western blot including: (1) the existence of a splice variant, (2) the quality of the loaded sample, (3) the protein extraction method, and (4) the protein transfer conditions. To achieve accurate results, you may need to systematically adjust the protein extraction method or the protein transfer conditions.

    • If the band’s MW is below the expected MW it could be due to a splice variant with a slightly different MW.
      • Heat the samples at 70°C for 10 min.
      • Increase the transfer time.
    • If the band’s MW is above the expected MW, it could be due to post-translational modifications.
    • In either event, you should use a blocking peptide as a negative control.

  • Some toxins and peptides are soluble in DMSO; you can find this information in the product specification section. For these products, prepare a concentrated stock solution first.

    1. Centrifuge vial (10,000 x g, 5 minutes) before adding solvent.
    2. Dissolve the lyophilized reagent in DMSO. We recommend keeping a concentrated stock solution at 1-10 mM (100-1000X higher than the final working concentration).
    3. Once the peptide is completely dissolved in DMSO, slowly dilute the peptide in pure water (or buffer) to the desired final working concentration.

    Note: We recommend that you maintain a DMSO concentration as low as possible. For cell assays, a final concentration of 0.1–0.5% DMSO (v/v) is considered acceptable. For other experiments, 5% DMSO (v/v) is recommended; adjust this according to your experimental requirements.

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378 Results
  • mHuwentoxin-IV
    Bioassay Tested
    mHuwentoxin-IV
    A potent and selective blocker of the neuronal NaV1.7 voltage-gated sodium channels
    • Product Code: STH-101
    • Short Description: A potent and selective blocker of the neuronal NaV1.7 voltage-gated sodium channels
    • Applications: Electrophysiology
    • MW: 4088.8 Da
  • Huwentoxin-IV
    Bioassay Tested
    Huwentoxin-IV
    A potent and selective blocker of the neuronal NaV1.7 voltage-gated sodium channels
    • Product Code: STH-100
    • Short Description: A potent and selective blocker of the neuronal NaV1.7 voltage-gated sodium channels
    • Applications: Electrophysiology
    • CAS No.: 526224-73-7
    • MW: 4106.8 Da
  • GsAF-II
    Bioassay Tested
    GsAF-II
    A potent gating modifier of tetrodotoxin-sensitive (TTX-s) neuronal voltage-gated sodium (NaV) channels that also blocks hERG1 potassium channels
    • Product Code: STG-350
    • Short Description: A potent gating modifier of tetrodotoxin-sensitive (TTX-s) neuronal voltage-gated sodium (NaV) channels that also blocks hERG1 potassium channels
    • Applications: Electrophysiology
    • MW: 3979.8 Da
  • GsAF-I
    Bioassay Tested
    GsAF-I
    A potent gating modifier of tetrodotoxin-sensitive (TTX-s) neuronal voltage-gated sodium (NaV) channels that also blocks hERG1 potassium channels
    • Product Code: STG-300
    • Short Description: A potent gating modifier of tetrodotoxin-sensitive (TTX-s) neuronal voltage-gated sodium (NaV) channels that also blocks hERG1 potassium channels
    • Applications: Electrophysiology
    • MW: 3707.5 Da
  • α-Conotoxin PeIA
    Bioassay Tested
    α-Conotoxin PeIA
    An antagonist of neuronal nAChRs (α9α10, α6-containing, and α3/β2) that also inhibits N-type (CaV2.2) calcium channels via GABA(B) receptor activation
    • Product Code: STC-970
    • Applications: Electrophysiology
    • CAS No.: 866876-88-2
    • MW: 1652 Da
  • Conantokin R
    Bioassay Tested
    Conantokin R
    A potent, competitive antagonist of NMDARs containing either the GluN2A or GluN2B receptor subunit
    • Product Code: STC-777
    • Applications: Electrophysiology
    • CAS No.: 202925-60-8
    • MW: 3098 Da
  • Conantokin G
    Bioassay Tested
    Conantokin G
    A selective and competitive antagonist of the GluN2B receptor
    • Product Code: STC-666
    • Short Description: A selective and competitive antagonist of the GluN2B receptor
    • Applications: Electrophysiology
    • CAS No.: 93438-65-4
    • MW: 2264.2 Da
  • µ-Conotoxin CnIIIC
    Bioassay Tested
    µ-Conotoxin CnIIIC
    A potent blocker of skeletal muscle NaV1.4 and neuronal NaV1.2 sodium channels, which also inhibits the α3/β2 nAChR
    • Product Code: STC-640
    • Applications: Electrophysiology
    • MW: 2376 Da
  • Chlorotoxin
    Chlorotoxin
    A potent scorpion toxin that preferentially binds to tumor cells by targeting multiple receptors including chloride channels,MMP-2, and Neuropilin-1
    • Product Code: STC-460
    • Applications: Cell-Based Assays, Electrophysiology, Calcium imaging assay
    • CAS No.: 163515-35-3
    • MW: 3995.8 Da
  • µ-Conotoxin SxIIIC
    Bioassay Tested
    µ-Conotoxin SxIIIC
    A potent blocker of multiple voltage-gated sodium NaV channels, showing highest affinity for the skeletal muscle NaV1.4 subtype
    • Product Code: STC-130
    • Applications: Electrophysiology
    • MW: 2437 Da
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