Every lot is tried & tested in a relevant biological assay.
Our Bioassay
- Smith, G.F. et al. (1967) Nature 216, 1134.
- Tellam, R. and Frieden, C. (1982) Biochemistry 21, 3207.
- Yahara, I. et al. (1982) J. Cell. Biol. 92, 69.
- Matsuyama, T. et al. (1991) J. Immunol. 146, 3736.
Protect from light.
- Alomone Labs Cytochalasin E inhibits actin polymerization in C6 glioma cells.Cells were incubated in the absence (A) or presence (B) of 10 µM Cytochalasin E (#C-550) for 1 h at 37°C. The figure shows dual staining using Rhodamine-conjugated-Palloidine for actin filament staining (red) and DAPI for nucleus staining (blue).
- Smith, G.F. et al. (1967) Nature 216, 1134.
- Tellam, R. and Frieden, C. (1982) Biochemistry 21, 3207.
- Yahara, I. et al. (1982) J. Cell Biol. 92, 69.
- Matsuyama, T. et al. (1991) J. Immunol. 146, 3736.
- McDonald, T.P. et al. (1995) J. Biol. Chem. 270, 30359.
- Baeker, T.R. et al. (1987) J. Immunol. 138, 2691.
Cytochalasins are a group of fungal toxin metabolites which bind to actin and alter its polymerization. Cytochalasins bind to the barbed end of the actin filament and prevent both the association and dissociation of actin subunits by inhibiting cell microtubule formation, cell division and cell migration.1-4
Cytochalasin E induced a rapid and sustained elevation of intracellular free Ca2+ in B lymphocytes by increasing the extracellular Ca2+ influx.5,6
Cytochalasin E (#C-550) is a highly pure, natural, and biologically active compound.
Applications
Citations
Specifications
Scientific Background
Related Products
Need Help With This Product?
Our reagent specialists are here to help you find the best product for your application. Please call or email us and we will be happy to help you find the right product for the job.
Call us at
+972 2587 2202 or Email Us