Somatostatin Receptor Type 3 Blocking Peptide (#BLP-SR003) is the original antigen used for immunization during Anti-Somatostatin Receptor Type 3 Antibody (#ASR-003) generation. The blocking peptide binds and ‘blocks’ Anti-Somatostatin Receptor Type 3 primary antibody, this makes it a good negative reagent control to help confirm antibody specificity in western blot and immunohistochemistry applications. This control is also often called a pre-adsorption control.
- Western blot analysis of rat brain lysate:
- Expression of SSTR3 in mouse cerebellumImmunohistochemical staining of mouse cerebellum with Anti-Somatostatin Receptor Type 3 Antibody (#ASR-003). A. SSTR3 appears in Purkinje cells (red, arrow points at an example). B. Staining of Purkinje nerve cells with mouse anti parvalbumin (a calcium binding protein, green). C. Confocal merge of SSTR3 and parvalbumin demonstrates the co-localization of these proteins in Purkinje cells (arrow points at a Purkinje cell pointed at in A and B).
- KVRSTTRRVRAPSC, corresponding to amino acid residues 233-246 of rat SSTR3 (Accession P30936).