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Blockers

Ca2+-Activated K+ Channels

Blockers

Ca2+-dependent K+ (KCa) channels are divided according to biophysical properties and gene homology into two main groups. KCa were first divided according to their single channel conductance, which represents the speed by which the K+ passes via the open channel. The first group consists of small and intermediate conductance channels (SK and IK respectively, the KCNN gene family). The second group is comprised of large/big conductance channels (called BKCa or maxiK, encoded by the slo or KCNMA1 gene).

Displaying 1 to 20 (out of 28 products)
  • Slotoxin

    A Blocker of KCa1.1 Channel

    Cat # STS-410
    MW 4086 Da.
    Target KCa1.1 K+ channels
    • Bioassay Tested
  • Apamin

    A Blocker of Small Conductance Ca2+-Activated K+ Channels (SK Type)

    Cat # STA-200
    MW 2028 Da.
    Target KCa2 K+ channels
    • Bioassay Tested
  • Apamin-Biotin

    A Blocker of Small Conductance Ca2+-Activated K+ Channels (SK Type) Conjugated to Biotin

    Cat # STA-200-B
    MW 2367 Da.
    Target KCa2 K+ channels
    • Bioassay Tested
  • Bupivacaine hydrochloride

    A Blocker of Neuronal NaV, KCa, and TREK-1 K2P Channels 

    Cat # B-125
    Source Synthetic
    MW 324.9
    Target NaV, KCa, K2P channels
    • Bioassay Tested
  • Charybdotoxin

    A Blocker of KV1.2, KV1.3 and KCa1.1 K+ Channels

    Cat # STC-325
    MW 4296 Da.
    Target KCa1.1, KV1.2, KV1.3 K+ channels
    • Bioassay Tested
  • Iberiotoxin

    A Potent and Specific Blocker of KCa1.1 K+ Channels

    Cat # STI-400
    MW 4230.9 Da.
    Target KCa1.1 K+ channels
    • Bioassay Tested
  • Kaliotoxin-1

    A Powerful Blocker of KCa1.1 and certain KV1 Channels

    Cat # STK-370
    MW 4150 Da.
    Target KCa1.1 and some KV1 Kchannels
    • Bioassay Tested
  • Maurotoxin

    A Potent Blocker of KCa and KV1 K+ Channels

    Cat # STM-340
    MW 3612 Da.
    Target KCa and KV1 K+ channels
    • Bioassay Tested
  • NS-6180

    A Potent Blocker of KCa3.1 Channel

    Cat # N-230
    Source Synthetic
    MW 323.3
    Target KCa3.1 channels
    • Bioassay Tested
  • NS8593

    A Blocker of KCa2 and TRPM7 Channels

    Cat # N-196
    Source Synthetic
    MW 263.3
    Target SK K+ channels, TRPM7
    • Bioassay Tested
  • NS8593 hydrochloride

    A Blocker of KCa2 and TRPM7 Channels

    Cat # N-195
    Source Synthetic
    MW 299.79
    Target SK K+ channels, TRPM7
    • Bioassay Tested
  • OsK-1 Toxin

    A Potent Blocker of KV1.3 and KCa3.1 K+ Channels

    Cat # STO-150
    MW 4205 Da.
    Target KV1.1, KV1.2, KV1.3, and KCa3.1 K+ channels
    • Bioassay Tested
  • Paxilline

    A Mycotoxin Blocker of KCa1.1 (BK) Channels and SERCA Pumps

    Cat # P-450
    Source Natural
    MW 435.6
    Target KCa K+ channels, SERCA pump
    • Bioassay Tested
  • Penitrem A

    A Blocker of KCa1.1 (BK) Channels

    Cat # P-650
    Source Natural
    MW 634.2
    Target KCa1.1 K+ channels
    • Bioassay Tested
  • Scyllatoxin

    A Potent Blocker of KCa2 (SK) K+ Channels

    Cat # STS-370
    MW 3423 Da.
    Target KCa2 K+ channels
    • Bioassay Tested
  • Tamapin

    A Blocker of KCa2 Channels

    Cat # STT-400
    MW 3458.16 Da.
    Target KCa2 K+ channels
    • Bioassay Tested
  • TRAM 34

    A Selective and Potent Blocker of KCa3.1 Channels

    Cat # T-105
    Source Synthetic
    MW 344.8
    Target KCa3.1 K+ channels
    • Bioassay Tested
  • Urotoxin

    A Super Potent Blocker of KV1.2 Channel

    Cat # STU-200
    MW 4012.7 Da.
    Target KV1.2, KV1.1, KV1.3, KCa3.1 channels
    • Bioassay Tested
  • Verruculogen

    A Blocker of KCa1.1 (BK) Channels

    Cat # V-500
    Source Natural
    MW 511.23
    Target KCa1.1 Kchannels
    • Bioassay Tested
  • Classical Ion Channel Blockers for Pain Research Explorer Kit

    A Screening Package of Classical Ion Channel Blockers for Pain Research Economically Priced

    Cat # EK-355

* See product page

Displaying 1 to 20 (out of 28 products)