L-type voltage-sensitive Ca2+ channels (CaV) on the plasma membrane of diverse cell types play a fundamental role in Ca2+ signaling …
Continue readingCell Biology
Involvement of Ca2+ in the Apoptotic Process – “Friends or Foes”
Over the past two decades, the ubiquitous position of Ca2+ signaling in cellular apoptosis has been carefully investigated. The body …
By Yossi Anis, Ph.D.
Continue reading Cell Death Modulators for in vitro Apoptosis Models
Until the beginning of 1980s, nerve cell necrosis was thought to responsible for nerve cell death in human brain, stroke …
By Alomone Labs
Continue reading Involvement of Ion Channels in Apoptosis
Involvement of ion channels in apoptosis is linked to critical aspects of this complex cellular process such as coordination of …
By Alon Meir, Ph.D.
Continue reading KATP Channels: Linking Cell Metabolism to Cell Excitability
ATP-sensitive K+ channels (KATP channels) were described nearly 20 years ago in membrane patches of isolated ventricular myocytes. Since then, …
By Noemí Bronstein-Sitton, Ph.D.
Continue reading Ca2+-Dependent K+ (KCa) Channels: At the Crossroads of Cell Metabolism
K+ channels are the largest and most diverse superfamily of ion channels. They are ubiquitously expressed in both excitatory and …
By Noemí Bronstein, Ph.D.
Continue reading The Involvement of Ion Channels in Cell Proliferation
The control of cell proliferation involves diverse signaling pathways, growth factors, and receptors. The involvement of ion channels in this …
By Phyllis Dan, Ph.D.
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