Anti-Bestrophin-1 (extracellular) Antibody
A Rabbit Polyclonal Antibody to Bestrophin-1 ChannelCat # ABC-001Type PolyclonalHost RabbitApplications ifc, ihc, lci, wb, icc*, ip*Reactivity h, m, r
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Alomone Labs FITC-conjugated extracellular antibodies offer you significant advantages. Skip cell permeabilization/fixation.
NOW you can conduct flow cytometry using live cells in ONE single step.
These novel antibodies save you valuable time and resources, while empowering your research results.
✓ Developed for flow cytometry (FACS)
✓ Tested with appropriate isotype control
✓ No need for secondary antibodies
✓ Conjugated to “extracellular” antibodies
✓ Cell-surface detection of proteins
✓ Permeabilization & cell fixation not required
✓ Time saving
Within our antibody portfolio, we gladly take on special requests for customized antibody labeling/conjugation.
Bestrophins were first found by genetic linkage of human-Bestrophin-1 (hBest1) to a juvenile form of macular degeneration called Best vitelliform macular dystrophy. To date Bestrophin 1-4 have been identified, although Bestrophin-3 and Bestrophin-4 have been observed only at the RNA level. In addition, splice variants of some of these Ca2+-activated Cl– channels (CaCCs) have also been detected. CaCCs are known to be involved in the regulation of olfaction, taste, phototransduction, and excitability in the nervous system. However, the molecular identity and functional role of CaCC in the brain have not been well established.