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Neurotrophin Receptors and Co-Receptors

BDNF and NT-4 belong to the neurotrophin family which also includes NGF and NT-3. These neurotrophins bind two groups of receptors. The p75NTR receptor is common to all four neurotrophins and is a member of the tumor necrosis factor receptor family. The tropomyosin-related kinase (Trk) receptors are receptor tyrosine kinases (RTKs) and three receptors form this family: TrkA, TrkB, and TrkC. TrkA is activated by NGF binding, TrkB by that of BDNF and NT-4, while TrkC is stimulated by the binding of NT-3.

  • Guinea Pig Anti-TrkB (extracellular) Antibody

    A Guinea Pig Polyclonal Antibody to TrkB

    Cat # ANT-019-GP
    Type Polyclonal
    Host Guinea Pig
    Applications ihc, wb, icc*, ip*
    Reactivity h, m, r
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