|Product Name||Cat #||Size|
|RTA-400||1 x 5 µg|
|STW-100||1 x 0.1 mg|
|RTA-150||1 x 5 µg|
|STA-420||1 x 50 µg|
|RTA-390||1 x 5 µg|
|C-180||1 x 50 mg|
|STC-325||1 x 0.1 mg|
|STC-660||1 x 5 µg|
|STC-650||1 x 5 µg|
CP 339818 hydrochloride
|C-115||1 x 5 mg|
|D-350||1 x 50 µg|
|D-360||1 x 35 µg|
|D-370||1 x 70 µg|
|D-380||1 x 70 µg|
|D-390||1 x 0.14 mg|
|D-400||1 x 10 µg|
|STH-500||1 x 10 µg|
|RTH-400||1 x 5 µg|
|STH-300||1 x 50 µg|
|STK-370||1 x 50 µg|
|STM-325||1 x 0.1 mg|
|STM-250||1 x 0.5 mg|
|M-206||1 x 1 g|
|STN-340||1 x 5 µg|
|RTO-150||1 x 5 µg|
|STP-500||1 x 50 µg|
ShK (Stichodactyla Toxin)
|STS-400||1 x 0.1 mg|
|STT-360||1 x 0.1 mg|
|T-145||1 x 5 mg|
|U-100||1 x 5 mg|
- Lyophilized Powder Lyophilized Powder
This product is freeze dried. All water molecules have been removed.
- Bioassay Tested Bioassay Tested
This antibody has undergone quality control and has been approved by our professional team.
- Shipped at Room Temp. Shipped at Room Temp.
This lyophilized product is shipped at room temperature. Please see its certificate of analysis for further storage instructions.
Alomone Labs is pleased to offer the Shaker (KV1) Channel Blocker Explorer Kit (#EK-107). This Explorer Kit is ideal for screening purposes.
K+ selective channels are some of the most widespread ion trafficking molecules in living organisms, with more than 70 genes encoding different K+ channels in humans. 38 of those genes encode members of the KV channel super family1. KV channels are composed of two types of protein subunits: the α subunit, which forms the pore and auxiliary (β) subunits. α subunits tetramerize in order to form a functional K+ conducting channel. The KV α subunit is a protein with six transmembrane (TM) domains and intracellular N- and C-termini. The most defined structural features are the extracellular loop between the fifth and sixth TM (which forms the K+ selectivity filter and the channel pore) and the fourth TM, which is positively charged and forms the voltage sensor of the protein2.
The pharmacological profile of KV channels is quite impressive. Due to the large number and types of functional KV channels, it became very important to identify the different native KV currents in different tissues, cell types and developmental stages. Therefore, molecules that can specifically bind KV channel components have become powerful tools in characterizing both the channel structure and its physiological role. Peptidyl toxins, mainly from scorpion and snake venoms, play a major role in identifying the various KV channels. Such toxins include dendrotoxins from the green and black mamba snakes and agitoxins from scorpions.
- Anti-KV1.1 (KCNA1) Antibody (#APC-009)
- Anti-KV1.2 (KCNA2) Antibody (#APC-010)
- Anti-KV1.3 (KCNA3) Antibody (#APC-002)
- Anti-KV1.3 (KCNA3) (extracellular) Antibody (#APC-101)
- Anti-KV1.4 Antibody (#APC-007)
- Anti-KV1.5 (KCNA5) Antibody (#APC-004)
- Anti-KV1.6 Antibody (#APC-003)
- Anti-KV1.7 Antibody (#APC-063)
- Anti-KV1.8 Antibody (#APC-157)
- Anti-KV2.1 Antibody (#APC-012)
- Anti-KV3.1b (KCNC1) Antibody (#APC-014)
- Anti-KV4.1 (KCND1) Antibody (#APC-119)
- Anti-KCNQ1 Antibody (#APC-022)
- Shaker (KV1) Channel Antibody Explorer Kit (#AK-219)
- Shaker (KV)-Related Channel Antibody Explorer Kit (#AK-220)
- Shaker (KV)-Related Channel Blocker Explorer Kit (#EK-108)