Adenosine Receptor Antibody Explorer Kit

A Screening Package of Adenosine Receptor Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-105
Sizes: 10 Vials
Last update: 28/03/2019

Alomone Labs is pleased to offer the Adenosine Receptor Antibody Explorer Kit (#AK-105). This Explorer Kit includes antibodies targeting Adenosine receptors along with their respective control peptide antigen. An ideal tool for screening purposes.

For research purposes only, not for human use
Compounds
Scientific Background
Scientific Background Adenosine is an endogenous nucleoside generated locally in tissues under conditions of hypoxia, ischemia, or inflammation. It modulates a variety of physiological functions in many tissues including brain and heart1,2. It exerts its action via four specific adenosine receptors (also named P1 purinergic receptors): A1-Adenosine Receptor (A1AR), A2A-Adenosine Receptor (A2AAR), A2B-Adenosine Receptor (A2BAR), and A3-Adenosine Receptor (A3AR). All are integral membrane proteins and members of the G-protein coupled receptor superfamily. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, a cytoplasmic carboxyl terminus, and a third intracellular loop that is important in binding G proteins1-3. The various adenosine receptors can be distinguished on the basis of their differential selectivity for adenosine analogs1-3.
References
  1. Okusa, M.D. (2002) Am. J. Physiol. 282, F10.
  2. Nakata, H. (1989) J. Biol. Chem. 264, 16545.
  3. Linden, J. (1991) FASEB J. 5, 2668.
Related Products